Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
1
Mixed / Neutral • confidence Minimal
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 24 • mentions 9 • links 113
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
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Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial.
The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial.
Efficacy and safety of fermented garlic extract on hepatic function in adults with elevated serum gamma-glutamyl transpeptidase levels: a double-blind, randomized, placebo-controlled trial.
Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention.
A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids.
Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis.
Effects of garlic extract on lipid profile in patients with coronary artery disease: A systematic review and meta-analysis of randomised clinical trials.
Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study.
Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension.
Hormone molecular biology and clinical investigation
Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial.
Randomized trial evaluating the effect of aged garlic extract with supplements versus placebo on adipose tissue surrogates for coronary atherosclerosis progression.
Improved microvascular reactivity after aged garlic extract intake is not mediated by hydrogen sulfide in older adults at risk for cardiovascular disease: a randomized clinical trial.
Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.
Budget-conscious (may prefer niacinamide as cheaper alternative): 1
No Effect
no noticeable effect: 1
Aged garlic extract (Kyolic) is the best-studied form. Food-based garlic adds synergistic benefits. | Step2: Insufficient empirical signal for a directional adjustment.
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Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.
Extracted from 4 dosing mentions across 3 PubMed studies (mg/day).
Imported legacy community score: 7.0/10 (heuristic mapping confidence 1.00).
Legacy community note: Respected NAD+ precursor with strong safety data. Some community members prefer NMN for potency. Niagen brand has loyal following. Less "exciting" than NMN marketing-wise but solid science.
Open source 5. Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial.
PUBMED • 2018 • Human evidence curation set
PMID 29576354 from Clinical nutrition ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 6. The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial.
PUBMED • 2016 • Human evidence curation set
PMID 26954484 from Journal of diabetes and its complications.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 7. Efficacy and safety of fermented garlic extract on hepatic function in adults with elevated serum gamma-glutamyl transpeptidase levels: a double-blind, randomized, placebo-controlled trial.
PUBMED • 2017 • Human evidence curation set
PMID 27743130 from European journal of nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 8. Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention.
PUBMED • 2012 • Human evidence curation set
PMID 22280901 from Clinical nutrition (Edinburgh, Scotland).
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 9. A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids.
PUBMED • 1996 • Human evidence curation set
PMID 8942410 from The American journal of clinical nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 10. Effects of garlic supplementation on serum inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.
PUBMED • 2020 • Human evidence curation set
PMID 32673835 from Diabetes & metabolic syndrome.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 11. The effect of aged garlic extract on the atherosclerotic process - a randomized double-blind placebo-controlled trial.
PUBMED • 2020 • Human evidence curation set
PMID 32349742 from BMC complementary medicine and therapies.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 12. Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study.
PUBMED • 2004 • Human evidence curation set
PMID 15726891 from Hiroshima journal of medical sciences.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 13. Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention.
PUBMED • 2018 • Human evidence curation set
PMID 29604599 from Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 14. Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials.
PUBMED • 2024 • Human evidence curation set
PMID 39437887 from Prostaglandins & other lipid mediators.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 15. Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis.
PUBMED • 2023 • Human evidence curation set
PMID 36640154 from Phytotherapy research : PTR.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 16. Effects of garlic extract on platelet aggregation: a randomized placebo-controlled double-blind study.
PUBMED • 1995 • Human evidence curation set
PMID 8582091 from Clinical and experimental pharmacology & physiology.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 17. Effects of garlic extract on lipid profile in patients with coronary artery disease: A systematic review and meta-analysis of randomised clinical trials.
PUBMED • 2021 • Human evidence curation set
PMID 34627133 from International journal of clinical practice.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 18. Nutraceuticals with a clinically detectable blood pressure-lowering effect: a review of available randomized clinical trials and their meta-analyses.
PUBMED • 2017 • Human evidence curation set
PMID 26852373 from British journal of clinical pharmacology.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 19. Does garlic reduce risk of colorectal cancer? A systematic review.
PUBMED • 2007 • Human evidence curation set
PMID 17885009 from The Journal of nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 20. Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study.
PUBMED • 2022 • Human evidence curation set
PMID 35276764 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 21. Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension.
PUBMED • 2024 • Human evidence curation set
PMID 39001718 from Hormone molecular biology and clinical investigation.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 22. Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial.
PUBMED • 2019 • Human evidence curation set
PMID 31511230 from BMJ (Clinical research ed.).
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 23. Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions.
PUBMED • 2006 • Human evidence curation set
PMID 16849680 from Journal of the National Cancer Institute.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 24. Randomized trial evaluating the effect of aged garlic extract with supplements versus placebo on adipose tissue surrogates for coronary atherosclerosis progression.
PUBMED • 2018 • Human evidence curation set
PMID 29140808 from Coronary artery disease.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 25. Improved microvascular reactivity after aged garlic extract intake is not mediated by hydrogen sulfide in older adults at risk for cardiovascular disease: a randomized clinical trial.
PUBMED • 2022 • Human evidence curation set
PMID 35505122 from European journal of nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 26. Aged Garlic Extract Modifies Human Immunity.
PUBMED • 2016 • Human evidence curation set
PMID 26764332 from The Journal of nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 27. A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans.
PUBMED • 2015 • Human evidence curation set
PMID 26423732 from The Journal of nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 28. Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.
PUBMED • 2023 • Human evidence curation set
PMID 37686723 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]
Open source 29. LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers.
RCT • 2024 • PubMed indexed study
PMID 39203947 from Nutrients.
Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]
Open source 30. Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial.
RCT • 2013 • PubMed indexed study
PMID 23169470 from European journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]
Open source 31. Aged garlic extract has potential suppressive effect on colorectal adenomas in humans.
RCT • 2006 • PubMed indexed study
PMID 16484573 from The Journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]
Open source 32. Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.
RCT • 2006 • PubMed indexed study
PMID 16484572 from The Journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]
Open source 33. Aged garlic extract may be safe for patients on warfarin therapy.
RCT • 2006 • PubMed indexed study
PMID 16484565 from The Journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]
Open source 34. A randomized factorial study of the effects of long-term garlic and micronutrient supplementation and of 2-wk antibiotic treatment for Helicobacter pylori infection on serum cholesterol and lipoproteins.
RCT • 2006 • PubMed indexed study
PMID 17023720 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]
Open source 35. Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions.
RCT • 2001 • PubMed indexed study
PMID 11238801 from The Journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]
Open source 36. Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods.
RCT • 2018 • PubMed indexed study
PMID 29937536 from Nutrients.
Outcome: Study design: RCT. Quality score: 7.9/10.[1322,1324,1365, etc.]
Open source 37. Garlic supplementation attenuates cycling exercise-induced oxidative inflammation but fails to improve time trial performance in healthy adults.
RCT • 2023 • PubMed indexed study
PMID 37170623 from Journal of the International Society of Sports Nutrition.
Outcome: Study design: RCT. Quality score: 7.8/10.[1322,1324,1365, etc.]
Open source 38. Oral post-exercise garlic extract supplementation enhances glycogen replenishment but does not up-regulate mitochondria biogenesis mRNA expression in human-exercised skeletal muscle.
RCT • 2024 • PubMed indexed study
PMID 38576169 from Journal of the International Society of Sports Nutrition.
Outcome: Study design: RCT. Quality score: 7.8/10.[1322,1324,1365, etc.]
Open source 39. No effect of garlic extract supplement on serum lipid levels in hypercholesterolemic subjects.
RCT • 2003 • PubMed indexed study
PMID 12948274 from Journal of the Medical Association of Thailand = Chotmaihet thangphaet.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 40. Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis.
RCT • 2013 • PubMed indexed study
PMID 23453866 from International journal of cardiology.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 41. Daily supplementation with aged garlic extract, but not raw garlic, protects low density lipoprotein against in vitro oxidation.
RCT • 1999 • PubMed indexed study
PMID 10217370 from Atherosclerosis.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 42. Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality.
RCT • 2012 • PubMed indexed study
PMID 22271764 from Journal of the National Cancer Institute.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 43. Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial.
RCT • 2009 • PubMed indexed study
PMID 19573556 from Preventive medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 44. Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial.
RCT • 2007 • PubMed indexed study
PMID 17325296 from Archives of internal medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 45. Aged garlic extract improves endothelial function in men with coronary artery disease.
RCT • 2005 • PubMed indexed study
PMID 16041725 from Phytotherapy research : PTR.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 46. Changes in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extract.
RCT • 1998 • PubMed indexed study
PMID 9641475 from Journal of cardiovascular pharmacology.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 47. Effect of short-term administration of garlic supplements on single-dose ritonavir pharmacokinetics in healthy volunteers.
RCT • 2003 • PubMed indexed study
PMID 12580992 from British journal of clinical pharmacology.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 48. Factorial trial of three interventions to reduce the progression of precancerous gastric lesions in Shandong, China: design issues and initial data.
RCT • 1998 • PubMed indexed study
PMID 9683311 from Controlled clinical trials.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 49. Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium.
RCT • 2010 • PubMed indexed study
PMID 20152239 from The American journal of cardiology.
Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]
Open source 50. Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans.
RCT • 2000 • PubMed indexed study
PMID 11053504 from The Journal of nutrition.
Outcome: Study design: CONTROLLED_TRIAL. Quality score: 7.1/10.[1322,1324,1365, etc.]
Open source 51. A factorial trial including garlic supplements assesses effect in reducing precancerous gastric lesions.
RCT • 2006 • PubMed indexed study
PMID 16484571 from The Journal of nutrition.
Outcome: Study design: CONTROLLED_TRIAL. Quality score: 7.1/10.[1322,1324,1365, etc.]
Open source 52. Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers.
RCT • 2003 • PubMed indexed study
PMID 12891227 from Clinical pharmacology and therapeutics.
Outcome: Study design: CONTROLLED_TRIAL. Quality score: 6.5/10.[1322,1324,1365, etc.]
Open source 53. Sickle cell anemia: a potential nutritional approach for a molecular disease.
RCT • 2000 • PubMed indexed study
PMID 10793299 from Nutrition (Burbank, Los Angeles County, Calif.).
Outcome: Study design: CONTROLLED_TRIAL. Quality score: 6.5/10.[1322,1324,1365, etc.]
Open source 54. Protective Effect of Garlic on Cellular Senescence in UVB-Exposed HaCaT Human Keratinocytes.
COHORT • 2016 • PubMed indexed study
PMID 27483310 from Nutrients.
Outcome: Study design: COHORT. Quality score: 5.9/10.[1322,1324,1365, etc.]
Open source 55. Efficacy, side effects, adherence, affordability, and procurement of dietary supplements for treating hypercholesterolemia: a narrative review.
COHORT • 2024 • PubMed indexed study
PMID 39563466 from Journal of health, population, and nutrition.
Outcome: Study design: COHORT. Quality score: 5.8/10.[1322,1324,1365, etc.]
Open source 56. Prevalence, Beliefs, and the Practice of the Use of Herbal and Dietary Supplements Among Adults in Saudi Arabia: An Observational Study.
COHORT • 2022 • PubMed indexed study
PMID 35596542 from Inquiry : a journal of medical care organization, provision and financing.
Outcome: Study design: COHORT. Quality score: 5.7/10.[1322,1324,1365, etc.]
Open source 57. Garlic: nature's protection against physiological threats.
PUBMED • 2009 • PubMed indexed study
PMID 19484634 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.5/10.[1322,1324,1365, etc.]
Open source 58. Mechanism of Action and Interaction of Garlic Extract and Established Therapeutics in Prostate Cancer.
PUBMED • 2025 • PubMed indexed study
PMID 40004239 from International journal of molecular sciences.
Outcome: Study design: OTHER. Quality score: 5.3/10.[1322,1324,1365, etc.]
Open source 59. Dual protection of aqueous garlic extract biomolecules against hemolysis and its oxidation products in preventing inflammation.
PUBMED • 2024 • PubMed indexed study
PMID 39097898 from Cellular and molecular biology (Noisy-le-Grand, France).
Outcome: Study design: OTHER. Quality score: 5.3/10.[1322,1324,1365, etc.]
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.2/10.[1322,1324,1365, etc.]
Open source 61. Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses.
PUBMED • 2015 • PubMed indexed study
PMID 25788027 from High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.2/10.[1322,1324,1365, etc.]
Open source 62. Intake of garlic and its bioactive components.
PUBMED • 2001 • PubMed indexed study
PMID 11238796 from The Journal of nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]
Open source 63. Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies.
PUBMED • 2001 • PubMed indexed study
PMID 11238803 from The Journal of nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]
Open source 64. Evidence of clinically relevant efficacy for dietary supplements and nutraceuticals.
PUBMED • 2013 • PubMed indexed study
PMID 23430658 from Current hypertension reports.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]
Open source 65. Historical perspective on garlic and cardiovascular disease.
PUBMED • 2001 • PubMed indexed study
PMID 11238800 from The Journal of nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]
Open source 66. Protection against Helicobacter pylori and other bacterial infections by garlic.
PUBMED • 2001 • PubMed indexed study
PMID 11238826 from The Journal of nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]
Open source 67. A Paradoxical Vasodilatory Nutraceutical Intervention for Prevention and Attenuation of Migraine-A Hypothetical Review.
PUBMED • 2020 • PubMed indexed study
PMID 32824835 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.0/10.[1322,1324,1365, etc.]
Open source 68. Anti-cancer activities of S-allylmercaptocysteine from aged garlic.
PUBMED • 2019 • PubMed indexed study
PMID 30704623 from Chinese journal of natural medicines.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.7/10.[1322,1324,1365, etc.]
Open source 69. The Emerging Role of Nutraceuticals and Phytochemicals in the Prevention and Treatment of Alzheimer's Disease.
PUBMED • 2020 • PubMed indexed study
PMID 32651325 from Journal of Alzheimer's disease : JAD.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.7/10.[1322,1324,1365, etc.]
Open source 70. Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells.
PUBMED • 2016 • PubMed indexed study
PMID 27734935 from Scientific reports.
Outcome: Study design: OTHER. Quality score: 4.7/10.[1322,1324,1365, etc.]
Open source 71. The Role of Adiponectin in Cardiometabolic Diseases: Effects of Nutritional Interventions.
PUBMED • 2016 • PubMed indexed study
PMID 26764331 from The Journal of nutrition.
Outcome: Study design: OTHER. Quality score: 4.7/10.[1322,1324,1365, etc.]
Open source 72. Nutraceuticals for blood pressure control.
PUBMED • 2015 • PubMed indexed study
PMID 26362125 from Annals of medicine.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.6/10.[1322,1324,1365, etc.]
Open source 73. Composition, stability, and bioavailability of garlic products used in a clinical trial.
PUBMED • 2005 • PubMed indexed study
PMID 16076102 from Journal of agricultural and food chemistry.
Outcome: Study design: OTHER. Quality score: 4.6/10.[1322,1324,1365, etc.]
Open source 74. Effects of garlic extract consumption on blood lipid and oxidant/antioxidant parameters in humans with high blood cholesterol.
PUBMED • 2004 • PubMed indexed study
PMID 15157944 from The Journal of nutritional biochemistry.
Outcome: Study design: OTHER. Quality score: 4.6/10.[1322,1324,1365, etc.]
Open source 75. The effects of garlic preparations against human tumor cell proliferation.
PUBMED • 1999 • PubMed indexed study
PMID 10228605 from Phytomedicine : international journal of phytotherapy and phytopharmacology.
Outcome: Study design: OTHER. Quality score: 4.6/10.[1322,1324,1365, etc.]
Open source 76. Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women.
PUBMED • 2002 • PubMed indexed study
PMID 11823573 from The Journal of nutrition.
Outcome: Study design: OTHER. Quality score: 4.6/10.[1322,1324,1365, etc.]
Open source 77. Health benefits of herbs and spices: the past, the present, the future.
PUBMED • 2006 • PubMed indexed study
PMID 17022438 from The Medical journal of Australia.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1322,1324,1365, etc.]
Open source 78. [Antifungal effect in selected natural compounds and probiotics and their possible use in prophylaxis of vulvovaginitis].
PUBMED • 2005 • PubMed indexed study
PMID 16180802 from Ceska gynekologie.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1322,1324,1365, etc.]
Open source 79. [New pharmacological activities of garlic and its constituents].
PUBMED • 1997 • PubMed indexed study
PMID 9503413 from Nihon yakurigaku zasshi. Folia pharmacologica Japonica.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1322,1324,1365, etc.]
Open source 80. Aged garlic extract enhances heme oxygenase-1 and glutamate-cysteine ligase modifier subunit expression via the nuclear factor erythroid 2-related factor 2-antioxidant response element signaling pathway in human endothelial cells.
PUBMED • 2016 • PubMed indexed study
PMID 26507778 from Nutrition research (New York, N.Y.).
Outcome: Study design: OTHER. Quality score: 4.4/10.[1322,1324,1365, etc.]
Open source 81. Investigation of taurine and aqueous garlic extract diet supplementation effect on the healing of rat osteoporotic fractures.
ANIMAL • 2023 • PubMed indexed study
PMID 36945935 from Turkish journal of medical sciences.
Outcome: Study design: ANIMAL. Quality score: 4.3/10.[1322,1324,1365, etc.]
Open source 82. Attenuation of chronic tension headache frequency and severity with daily L-arginine and aged garlic extract dietary supplementation.
MECHANISTIC • 2022 • PubMed indexed study
PMID 34302129 from European journal of clinical nutrition.
Outcome: Study design: CASE_REPORT. Quality score: 4.3/10.[1322,1324,1365, etc.]
Open source 83. Resolution of non-psychogenic epileptic-like seizures utilizing a vasodilatory and anti-inflammatory dietary intervention.
MECHANISTIC • 2016 • PubMed indexed study
PMID 27245208 from European journal of clinical nutrition.
Outcome: Study design: CASE_REPORT. Quality score: 4.2/10.[1322,1324,1365, etc.]
Open source 84. Protective Effects of AGE and Its Components on Neuroinflammation and Neurodegeneration.
PUBMED • 2016 • PubMed indexed study
PMID 27263111 from Neuromolecular medicine.
Outcome: Study design: OTHER. Quality score: 4.1/10.[1322,1324,1365, etc.]
Open source 85. Garlic extract in bladder cancer prevention: Evidence from T24 bladder cancer cell xenograft model, tissue microarray, and gene network analysis.
PUBMED • 2017 • PubMed indexed study
PMID 28498422 from International journal of oncology.
Outcome: Study design: OTHER. Quality score: 4.1/10.[1322,1324,1365, etc.]
Open source 86. Dehydrodiconiferyl alcohol suppresses monocyte adhesion to endothelial cells by attenuation of JNK signaling pathway.
PUBMED • 2015 • PubMed indexed study
PMID 26271597 from Biochemical and biophysical research communications.
Outcome: Study design: OTHER. Quality score: 4.1/10.[1322,1324,1365, etc.]
Open source 87. HIV protease inhibitors: garlic supplements and first-pass intestinal metabolism impact on the therapeutic efficacy.
PUBMED • 2010 • PubMed indexed study
PMID 21104925 from Biopharmaceutics & drug disposition.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 88. Garlic flavonoids and organosulfur compounds: impact on the hepatic pharmacokinetics of saquinavir and darunavir.
PUBMED • 2010 • PubMed indexed study
PMID 20930421 from Drug metabolism and pharmacokinetics.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 89. Inhibitory effect of whole strawberries, garlic juice or kale juice on endogenous formation of N-nitrosodimethylamine in humans.
PUBMED • 2002 • PubMed indexed study
PMID 12175517 from Cancer letters.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 90. The mechanisms responsible for garlic - drug interactions and their in vivo relevance.
PUBMED • 2013 • PubMed indexed study
PMID 21838705 from Current drug metabolism.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 91. Urinary excretion of N-acetyl-S-allyl-L-cysteine upon garlic consumption by human volunteers.
PUBMED • 1996 • PubMed indexed study
PMID 8870956 from Archives of toxicology.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 92. Testing garlic for possible anti-ageing effects on long-term growth characteristics, morphology and macromolecular synthesis of human fibroblasts in culture.
PUBMED • 1994 • PubMed indexed study
PMID 7526077 from Journal of ethnopharmacology.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 93. Aged garlic extract restores nitric oxide bioavailability in cultured human endothelial cells even under conditions of homocysteine elevation.
PUBMED • 2013 • PubMed indexed study
PMID 23127645 from Journal of ethnopharmacology.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 94. Kyolic and Pycnogenol increase human growth hormone secretion in genetically-engineered keratinocytes.
PUBMED • 2002 • PubMed indexed study
PMID 12127300 from Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 95. A gas chromatography-mass spectrometry method for the quantitation of N-nitrosoproline and N-acetyl-S-allylcysteine in human urine: application to a study of the effects of garlic consumption on nitrosation.
PUBMED • 2009 • PubMed indexed study
PMID 19643074 from Analytical biochemistry.
Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]
Open source 96. Garlic inhibits microsomal triglyceride transfer protein gene expression in human liver and intestinal cell lines and in rat intestine.
ANIMAL • 2002 • PubMed indexed study
PMID 12042427 from The Journal of nutrition.
Outcome: Study design: ANIMAL. Quality score: 3.6/10.[1322,1324,1365, etc.]
Open source 97. In vitro interactions between aged garlic extract and drugs used for the treatment of cardiovascular and diabetic patients.
IN_VITRO • 2010 • PubMed indexed study
PMID 20140680 from European journal of nutrition.
Outcome: Study design: IN_VITRO. Quality score: 3.1/10.[1322,1324,1365, etc.]
Open source 98. In vitro effects of aged garlic extract and other nutritional supplements on sickle erythrocytes.
IN_VITRO • 2001 • PubMed indexed study
PMID 11238822 from The Journal of nutrition.
Outcome: Study design: IN_VITRO. Quality score: 3.1/10.[1322,1324,1365, etc.]
Open source 99. The influence of aged garlic extract on the uptake of saquinavir and darunavir into HepG2 cells and rat liver slices.
ANIMAL • 2010 • PubMed indexed study
PMID 20610890 from Drug metabolism and pharmacokinetics.
Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1322,1324,1365, etc.]
Open source 100. Renoprotective effect of aged garlic extract in streptozotocin-induced diabetic rats.
ANIMAL • 2013 • PubMed indexed study
PMID 23543654 from Indian journal of pharmacology.
Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1322,1324,1365, etc.]
Open source 101. Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet.
ANIMAL • 2000 • PubMed indexed study
PMID 10882191 from Prostaglandins, leukotrienes, and essential fatty acids.
Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1322,1324,1365, etc.]
Open source 102. In Vitro, In Vivo, and In Silico Investigation of Synbiotic-Mediated Activation of PPAR-α Curtails Nonalcoholic Steatohepatitis (NASH) in Wistar Rats by Inhibiting PNPLA3/SREBP1-c Lead Inflammatory Injury of Hepatic Cells.
IN_VITRO • 2025 • PubMed indexed study
PMID 40017524 from Mediators of inflammation.
Outcome: Study design: IN_VITRO. Quality score: 2.8/10.[1322,1324,1365, etc.]
Open source 103. Helicobacter pylori--in vitro susceptibility to garlic (Allium sativum) extract.
IN_VITRO • 1997 • PubMed indexed study
PMID 9121937 from Nutrition and cancer.
Outcome: Study design: IN_VITRO. Quality score: 2.5/10.[1322,1324,1365, etc.]
Open source 104. Transwell-grown HepG2 cell monolayers as in vitro permeability model to study drug-drug or drug-food interactions.
IN_VITRO • 2011 • PubMed indexed study
PMID 21138349 from Journal of medicinal food.
Outcome: Study design: IN_VITRO. Quality score: 2.5/10.[1322,1324,1365, etc.]