Skip to main content
Enhanced Health AI
QuizMy PlanCalendarEvidenceSources
Session check

© 2026 Enhanced Health AI

MD-Designed No Data Soldv0.15.25
QuizSearchEvidenceSourcesHow We ScorePricingTermsPrivacy
Back to Database

Supplement

Aged Garlic Extract (Allicin)

Organosulfur compounds (allicin, S-allylcysteine) inhibit cholesterol synthesis, provide vasodilation via H₂S/NO pathways, antimicrobial activity, and immunomodulation.[1322,1324,1365, etc.]

Superscript reference numbers link to the Sources bibliography.

Strong Evidence
Heart HealthImmune SupportInflammationBlood Sugaralias: AGEalias: Kyolicalias: allicinalias: garlic supplement
cardioimmunemetabolic

Composite Rating

3.8/5

Blends evidence depth, community direction, safety friction, and completeness.

Evidence Intensity

100/100

High depth from human/RCT/meta counts

Community Direction

1

Mixed / Neutral • confidence Minimal

Safety Friction

100/100

High signal from adverse/interaction markers

Data Completeness

100%

Studies 24 • mentions 9 • links 113

Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.

FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.

If you are experiencing a medical emergency, call 911 or your local emergency number immediately.

Implementation Blueprint

Goal alignment: Heart Health, Immune Support, Inflammation, Blood Sugar.[506,654,878, etc.]

Dose guide: Human-study daily dose: 1 mg-250 mg/day (higher-confidence extraction from PubMed abstracts)..[506,654,878, etc.]

Category: botanical.[506,654,878, etc.]

Category

Botanical

Evidence Tier

ROBUST

Daily Guide

Human-study daily dose: 1 mg-250 mg/day (higher-confidence extraction from PubMed abstracts).

Dosing Guide

Human-study daily dose: 1 mg-250 mg/day (higher-confidence extraction from PubMed abstracts).[1322,1324,1365, etc.]

Safety and Pitfalls

  • Aged garlic extract (Kyolic) is odorless and best tolerated. Raw garlic more likely to cause GI upset.[506,654,878, etc.]
  • Potential side effect: garlic breath/body odor[506,654,878, etc.]
  • Potential side effect: heartburn[506,654,878, etc.]
  • Potential side effect: GI upset[506,654,878, etc.]
  • Use caution with condition: bleeding disorders[506,654,878, etc.]
  • Use caution with condition: upcoming surgery (stop 2 weeks prior)[506,654,878, etc.]
  • Interaction check: anticoagulants (warfarin, NOAC)[506,654,878, etc.]
  • Interaction check: HIV protease inhibitors (saquinavir)[506,654,878, etc.]
  • Legacy caution group: Active cancer[506,654,878, etc.]
  • Legacy caution group: Budget-conscious (may prefer niacinamide as cheaper alternative)[506,654,878, etc.]

At-A-Glance Evidence Architecture[1322,1324,1365, etc.]

Clinical Depth

Humans: 100 • RCTs: 39 • Meta: 5

Cohort / Real-World

Cohort signals: 0

Safety Markers

Adverse signals: 150 • Interactions: 60

Evidence Tracking

Freshness, trend, and study timeline for this item

Evidence Tracking

Status

New Evidence

Trend

→ Stable evidence base

Depth

219 total studies · 8 recent

Timeline

19942025

Top Signal Metrics[1322,1324,1365, etc.]

Animal-only studies

402

In vitro / tissue

244

Total indexed

219

Safety adverse signals

150

Human studies

100

Interaction signals

60

Community Direction Mix[506,654,878, etc.]

Weighted direction score: 1 (Mixed / Neutral)

Benefit4 (44%)
Adverse3 (33%)
No Effect1 (11%)
Mixed1 (11%)

Evidence Quality Summary[1322,1324,1365, etc.]

≥2 meta-analyses OR (≥5 RCTs AND ≥25 human studies).

Animal-only studies

402

In vitro / tissue

244

Total indexed

219

Safety adverse signals

150

Human studies

100

Interaction signals

60

Randomized trials

39

Meta-analyses

5

Study Type Breakdown

Distribution of evidence by study design strength

Meta-AnalysesLevel 1a5
Randomized TrialsLevel 1b39
Human Studies (other)Level 3-456
All IndexedAll levels219
100

Evidence Strength: High

Composite of study volume, RCTs, and meta-analyses

Top Human Studies[1322,1324,1365, etc.]

PMID 29576354 • 2018 Apr

Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial.

Clinical nutrition ESPEN

Open PubMed

PMID 26954484 • 2016 May-Jun

The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial.

Journal of diabetes and its complications

Open PubMed

PMID 27743130 • 2017 Aug

Efficacy and safety of fermented garlic extract on hepatic function in adults with elevated serum gamma-glutamyl transpeptidase levels: a double-blind, randomized, placebo-controlled trial.

European journal of nutrition

Open PubMed

PMID 22280901 • 2012 Jun

Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention.

Clinical nutrition (Edinburgh, Scotland)

Open PubMed

PMID 8942410 • 1996 Dec

A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids.

The American journal of clinical nutrition

Open PubMed

PMID 32673835 • 2020 Sep-Oct

Effects of garlic supplementation on serum inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.

Diabetes & metabolic syndrome

Open PubMed

PMID 32349742 • 2020 Apr 29

The effect of aged garlic extract on the atherosclerotic process - a randomized double-blind placebo-controlled trial.

BMC complementary medicine and therapies

Open PubMed

PMID 15726891 • 2004 Dec

Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study.

Hiroshima journal of medical sciences

Open PubMed

PMID 29604599 • 2018 Jun

Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Open PubMed

PMID 39437887 • 2024 Dec

Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials.

Prostaglandins & other lipid mediators

Open PubMed

PMID 36640154 • 2023 Jun

Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis.

Phytotherapy research : PTR

Open PubMed

PMID 8582091 • 1995 Jun-Jul

Effects of garlic extract on platelet aggregation: a randomized placebo-controlled double-blind study.

Clinical and experimental pharmacology & physiology

Open PubMed

PMID 34627133 • 2021 Dec

Effects of garlic extract on lipid profile in patients with coronary artery disease: A systematic review and meta-analysis of randomised clinical trials.

International journal of clinical practice

Open PubMed

PMID 26852373 • 2017 Jan

Nutraceuticals with a clinically detectable blood pressure-lowering effect: a review of available randomized clinical trials and their meta-analyses.

British journal of clinical pharmacology

Open PubMed

PMID 17885009 • 2007 Oct

Does garlic reduce risk of colorectal cancer? A systematic review.

The Journal of nutrition

Open PubMed

PMID 35276764 • 2022 Jan 18

Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study.

Nutrients

Open PubMed

PMID 39001718 • 2024 Dec 1

Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension.

Hormone molecular biology and clinical investigation

Open PubMed

PMID 31511230 • 2019 Sep 11

Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial.

BMJ (Clinical research ed.)

Open PubMed

PMID 16849680 • 2006 Jul 19

Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions.

Journal of the National Cancer Institute

Open PubMed

PMID 29140808 • 2018 Jun

Randomized trial evaluating the effect of aged garlic extract with supplements versus placebo on adipose tissue surrogates for coronary atherosclerosis progression.

Coronary artery disease

Open PubMed

PMID 35505122 • 2022 Oct

Improved microvascular reactivity after aged garlic extract intake is not mediated by hydrogen sulfide in older adults at risk for cardiovascular disease: a randomized clinical trial.

European journal of nutrition

Open PubMed

PMID 26764332 • 2016 Feb

Aged Garlic Extract Modifies Human Immunity.

The Journal of nutrition

Open PubMed

PMID 26423732 • 2015 Nov

A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans.

The Journal of nutrition

Open PubMed

PMID 37686723 • 2023 Aug 23

Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.

Nutrients

Open PubMed

Community Report Frequency[506,654,878, etc.]

Benefit reports: 4

Adverse reports: 3

No-effect reports: 1

Mixed reports: 1

Unclear reports: 0

Signal confidence: 0.00

Top Reported Effects[506,654,878, etc.]

Benefits

  • NAD+ elevation: 1
  • Cellular energy support: 1
  • Healthy aging: 1
  • Cardiovascular function: 1
  • Metabolic health: 1
  • Neuroprotection: 1

Adverse

  • Active cancer: 1
  • Budget-conscious (may prefer niacinamide as cheaper alternative): 1

No Effect

  • no noticeable effect: 1

Aged garlic extract (Kyolic) is the best-studied form. Food-based garlic adds synergistic benefits. | Step2: Insufficient empirical signal for a directional adjustment.

Reddit evidence: 0 mentions (confidence 0.00).

Amazon signal: 0 products scanned (confidence 0.00).

GNC signal: 0 products scanned (confidence 0.00) [BLOCKED].

PerimeterX / captcha block encountered.

Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=%22garlic%20extract%22%20(supplement%20OR%20dosage%20OR%20stack%20OR%20side%20effects%20OR%20review)%20(subreddit%3ASupplements%20OR%20subreddit%3ANootropics%20OR%20subreddit%3ABiohackers%20OR%20subreddit%3Alongevity%20OR%20subreddit%3ANutrition%20OR%20subreddit%3AHubermanLab%20OR%20subreddit%3ASleep%20OR%20subreddit%3AFitness%20OR%20subreddit%3Aketoscience%20OR%20subreddit%3AStackAdvice)

Fallback search failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=comments&t=all&limit=16&q=%22garlic%20extract%22%20(supplement%20OR%20capsule%20OR%20powder%20OR%20experience%20OR%20results%20OR%20side%20effects)

Broad search failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=new&t=all&limit=16&q=garlic%20extract

Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.

Human-study daily dose signal: 1 mg-250 mg/day (confidence HIGH).

Extracted from 4 dosing mentions across 3 PubMed studies (mg/day).

Imported legacy community score: 7.0/10 (heuristic mapping confidence 1.00).

Legacy community note: Respected NAD+ precursor with strong safety data. Some community members prefer NMN for potency. Niagen brand has loyal following. Less "exciting" than NMN marketing-wise but solid science.

Community Insights[506,654,878, etc.]

Sentiment Score

0.24/100

Benefit Mentions

  • blood pressure reduction
  • fewer colds
  • cholesterol support
  • affordable

Adverse Mentions

  • garlic smell
  • GI upset with raw
  • slow onset

Best Responders

No responder profile recorded.

Community Evidence Examples[506,654,878, etc.]

aggregate • benefit

Aggregate community signal: 9 directional mentions (benefit 4, adverse 3, no-effect 1, mixed 1).

Open mention

Retail Signal Examples

amazon

Amazon search for Aged Garlic Extract (Allicin)

Rating: n/a | Reviews: n/a

Open product

Primary Source Links

Evidence Sources

  • https://pubmed.ncbi.nlm.nih.gov/?term=(%22garlic%20extract%22)%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)
  • https://pubmed.ncbi.nlm.nih.gov/?term=(%22garlic%20extract%22)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)
  • https://pubmed.ncbi.nlm.nih.gov/?term=(%22garlic%20extract%22)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)%20AND%20randomized%20controlled%20trial%5BPublication%20Type%5D
  • https://pubmed.ncbi.nlm.nih.gov/?term=(%22garlic%20extract%22)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)%20AND%20meta-analysis%5BPublication%20Type%5D
  • https://pubmed.ncbi.nlm.nih.gov/?term=(%22garlic%20extract%22)%20AND%20humans%5BMeSH%20Terms%5D%20AND%20(supplement*%5BTitle%2FAbstract%5D%20OR%20supplementation%5BTitle%2FAbstract%5D%20OR%20intake%5BTitle%2FAbstract%5D%20OR%20dietary%20supplements%5BMeSH%20Terms%5D)%20AND%202018%3A3000%5Bpdat%5D
  • https://pubmed.ncbi.nlm.nih.gov/29576354/
  • https://pubmed.ncbi.nlm.nih.gov/26954484/
  • https://pubmed.ncbi.nlm.nih.gov/27743130/
  • https://pubmed.ncbi.nlm.nih.gov/22280901/
  • https://pubmed.ncbi.nlm.nih.gov/8942410/
  • https://pubmed.ncbi.nlm.nih.gov/32673835/
  • https://pubmed.ncbi.nlm.nih.gov/32349742/
  • https://pubmed.ncbi.nlm.nih.gov/15726891/
  • https://pubmed.ncbi.nlm.nih.gov/29604599/
  • https://pubmed.ncbi.nlm.nih.gov/39437887/
  • https://pubmed.ncbi.nlm.nih.gov/36640154/
  • https://pubmed.ncbi.nlm.nih.gov/8582091/
  • https://pubmed.ncbi.nlm.nih.gov/34627133/
  • https://pubmed.ncbi.nlm.nih.gov/26852373/
  • https://pubmed.ncbi.nlm.nih.gov/17885009/

Community Sources

  • https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=%22garlic%20extract%22%20(supplement%20OR%20dosage%20OR%20stack%20OR%20side%20effects%20OR%20review)%20(subreddit%3ASupplements%20OR%20subreddit%3ANootropics%20OR%20subreddit%3ABiohackers%20OR%20subreddit%3Alongevity%20OR%20subreddit%3ANutrition%20OR%20subreddit%3AHubermanLab%20OR%20subreddit%3ASleep%20OR%20subreddit%3AFitness%20OR%20subreddit%3Aketoscience%20OR%20subreddit%3AStackAdvice)
  • https://old.reddit.com/search.json?raw_json=1&sort=comments&t=all&limit=16&q=%22garlic%20extract%22%20(supplement%20OR%20capsule%20OR%20powder%20OR%20experience%20OR%20results%20OR%20side%20effects)
  • https://old.reddit.com/search.json?raw_json=1&sort=new&t=all&limit=16&q=garlic%20extract
  • https://www.reddit.com/search/?q=Aged%20Garlic%20Extract%20(Allicin)

Scientific Evidence Notes[1322,1324,1365, etc.]

1. Garlic supplementation and blood pressure: MA of 20 RCTs

META_ANALYSIS • 2015 • Adults

20 RCTs with 970 hypertensive subjects.

Outcome: Garlic significantly reduced SBP by −8.3 mmHg and DBP by −5.5 mmHg in hypertensives; Kyolic aged extract most studied.[1322,1324,1365, etc.]

Open source
2. Garlic and total cholesterol: MA of 39 RCTs

META_ANALYSIS • 2013 • Adults

39 RCTs with 2298 subjects.

Outcome: Garlic reduced total cholesterol by −17 mg/dL (−8%) and LDL by −9 mg/dL after 2+ months of supplementation.[1322,1324,1365, etc.]

Open source
3. Garlic and common cold prevention: Cochrane review

META_ANALYSIS • 2014 • Adults

8 studies with 735 subjects.

Outcome: Daily garlic supplementation reduced cold incidence (RR 0.56) but evidence quality was moderate; consistent immune modulation signal.[1322,1324,1365, etc.]

Open source
4. PubMed evidence summary: Garlic Extract

PUBMED • Humans + preclinical triage

Counts aggregated from automated literature sweep and tiering rules.

Outcome: Tier HIGH; humans 100, RCTs 39, meta-analyses 5.[1322,1324,1365, etc.]

Open source
5. Aged garlic extract supplementation modifies inflammation and immunity of adults with obesity: A randomized, double-blind, placebo-controlled clinical trial.

PUBMED • 2018 • Human evidence curation set

PMID 29576354 from Clinical nutrition ESPEN.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
6. The effects of garlic extract upon endothelial function, vascular inflammation, oxidative stress and insulin resistance in adults with type 2 diabetes at high cardiovascular risk. A pilot double blind randomized placebo controlled trial.

PUBMED • 2016 • Human evidence curation set

PMID 26954484 from Journal of diabetes and its complications.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
7. Efficacy and safety of fermented garlic extract on hepatic function in adults with elevated serum gamma-glutamyl transpeptidase levels: a double-blind, randomized, placebo-controlled trial.

PUBMED • 2017 • Human evidence curation set

PMID 27743130 from European journal of nutrition.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
8. Supplementation with aged garlic extract improves both NK and γδ-T cell function and reduces the severity of cold and flu symptoms: a randomized, double-blind, placebo-controlled nutrition intervention.

PUBMED • 2012 • Human evidence curation set

PMID 22280901 from Clinical nutrition (Edinburgh, Scotland).

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
9. A double-blind crossover study in moderately hypercholesterolemic men that compared the effect of aged garlic extract and placebo administration on blood lipids.

PUBMED • 1996 • Human evidence curation set

PMID 8942410 from The American journal of clinical nutrition.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
10. Effects of garlic supplementation on serum inflammatory markers: A systematic review and meta-analysis of randomized controlled trials.

PUBMED • 2020 • Human evidence curation set

PMID 32673835 from Diabetes & metabolic syndrome.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
11. The effect of aged garlic extract on the atherosclerotic process - a randomized double-blind placebo-controlled trial.

PUBMED • 2020 • Human evidence curation set

PMID 32349742 from BMC complementary medicine and therapies.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
12. Effects of aged garlic extract (AGE) on colorectal adenomas: a double-blinded study.

PUBMED • 2004 • Human evidence curation set

PMID 15726891 from Hiroshima journal of medical sciences.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
13. Garlic extract favorably modifies markers of endothelial function in obese patients -randomized double blind placebo-controlled nutritional intervention.

PUBMED • 2018 • Human evidence curation set

PMID 29604599 from Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
14. Effects of aged garlic extract on blood pressure in hypertensive patients: A systematic review and meta-analysis of randomized controlled trials.

PUBMED • 2024 • Human evidence curation set

PMID 39437887 from Prostaglandins & other lipid mediators.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
15. Effect of garlic extract on markers of lipid metabolism and inflammation in coronary artery disease (CAD) patients: A systematic review and meta-analysis.

PUBMED • 2023 • Human evidence curation set

PMID 36640154 from Phytotherapy research : PTR.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
16. Effects of garlic extract on platelet aggregation: a randomized placebo-controlled double-blind study.

PUBMED • 1995 • Human evidence curation set

PMID 8582091 from Clinical and experimental pharmacology & physiology.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
17. Effects of garlic extract on lipid profile in patients with coronary artery disease: A systematic review and meta-analysis of randomised clinical trials.

PUBMED • 2021 • Human evidence curation set

PMID 34627133 from International journal of clinical practice.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
18. Nutraceuticals with a clinically detectable blood pressure-lowering effect: a review of available randomized clinical trials and their meta-analyses.

PUBMED • 2017 • Human evidence curation set

PMID 26852373 from British journal of clinical pharmacology.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
19. Does garlic reduce risk of colorectal cancer? A systematic review.

PUBMED • 2007 • Human evidence curation set

PMID 17885009 from The Journal of nutrition.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
20. Effects of an Optimized Aged Garlic Extract on Cardiovascular Disease Risk Factors in Moderate Hypercholesterolemic Subjects: A Randomized, Crossover, Double-Blind, Sustainedand Controlled Study.

PUBMED • 2022 • Human evidence curation set

PMID 35276764 from Nutrients.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
21. Randomized, double-blind clinical trial evaluating the impact of freeze-dried garlic extract capsules on blood pressure, lipid profile, and nitric oxide levels in individuals at risk for hypertension.

PUBMED • 2024 • Human evidence curation set

PMID 39001718 from Hormone molecular biology and clinical investigation.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
22. Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial.

PUBMED • 2019 • Human evidence curation set

PMID 31511230 from BMJ (Clinical research ed.).

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
23. Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions.

PUBMED • 2006 • Human evidence curation set

PMID 16849680 from Journal of the National Cancer Institute.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
24. Randomized trial evaluating the effect of aged garlic extract with supplements versus placebo on adipose tissue surrogates for coronary atherosclerosis progression.

PUBMED • 2018 • Human evidence curation set

PMID 29140808 from Coronary artery disease.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
25. Improved microvascular reactivity after aged garlic extract intake is not mediated by hydrogen sulfide in older adults at risk for cardiovascular disease: a randomized clinical trial.

PUBMED • 2022 • Human evidence curation set

PMID 35505122 from European journal of nutrition.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
26. Aged Garlic Extract Modifies Human Immunity.

PUBMED • 2016 • Human evidence curation set

PMID 26764332 from The Journal of nutrition.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
27. A Single Meal Containing Raw, Crushed Garlic Influences Expression of Immunity- and Cancer-Related Genes in Whole Blood of Humans.

PUBMED • 2015 • Human evidence curation set

PMID 26423732 from The Journal of nutrition.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
28. Antihypertensive Effects of an Optimized Aged Garlic Extract in Subjects with Grade I Hypertension and Antihypertensive Drug Therapy: A Randomized, Triple-Blind Controlled Trial.

PUBMED • 2023 • Human evidence curation set

PMID 37686723 from Nutrients.

Outcome: See linked PubMed abstract for methods and outcomes.[1322,1324,1365, etc.]

Open source
29. LDL-Cholesterol-Lowering Effects of a Dietary Supplement Containing Onion and Garlic Extract Used in Healthy Volunteers.

RCT • 2024 • PubMed indexed study

PMID 39203947 from Nutrients.

Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]

Open source
30. Aged garlic extract reduces blood pressure in hypertensives: a dose-response trial.

RCT • 2013 • PubMed indexed study

PMID 23169470 from European journal of clinical nutrition.

Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]

Open source
31. Aged garlic extract has potential suppressive effect on colorectal adenomas in humans.

RCT • 2006 • PubMed indexed study

PMID 16484573 from The Journal of nutrition.

Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]

Open source
32. Aged garlic extract prevents a decline of NK cell number and activity in patients with advanced cancer.

RCT • 2006 • PubMed indexed study

PMID 16484572 from The Journal of nutrition.

Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]

Open source
33. Aged garlic extract may be safe for patients on warfarin therapy.

RCT • 2006 • PubMed indexed study

PMID 16484565 from The Journal of nutrition.

Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]

Open source
34. A randomized factorial study of the effects of long-term garlic and micronutrient supplementation and of 2-wk antibiotic treatment for Helicobacter pylori infection on serum cholesterol and lipoproteins.

RCT • 2006 • PubMed indexed study

PMID 17023720 from The American journal of clinical nutrition.

Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]

Open source
35. Aged garlic extract, a modulator of cardiovascular risk factors: a dose-finding study on the effects of AGE on platelet functions.

RCT • 2001 • PubMed indexed study

PMID 11238801 from The Journal of nutrition.

Outcome: Study design: RCT. Quality score: 8.1/10.[1322,1324,1365, etc.]

Open source
36. Allicin Bioavailability and Bioequivalence from Garlic Supplements and Garlic Foods.

RCT • 2018 • PubMed indexed study

PMID 29937536 from Nutrients.

Outcome: Study design: RCT. Quality score: 7.9/10.[1322,1324,1365, etc.]

Open source
37. Garlic supplementation attenuates cycling exercise-induced oxidative inflammation but fails to improve time trial performance in healthy adults.

RCT • 2023 • PubMed indexed study

PMID 37170623 from Journal of the International Society of Sports Nutrition.

Outcome: Study design: RCT. Quality score: 7.8/10.[1322,1324,1365, etc.]

Open source
38. Oral post-exercise garlic extract supplementation enhances glycogen replenishment but does not up-regulate mitochondria biogenesis mRNA expression in human-exercised skeletal muscle.

RCT • 2024 • PubMed indexed study

PMID 38576169 from Journal of the International Society of Sports Nutrition.

Outcome: Study design: RCT. Quality score: 7.8/10.[1322,1324,1365, etc.]

Open source
39. No effect of garlic extract supplement on serum lipid levels in hypercholesterolemic subjects.

RCT • 2003 • PubMed indexed study

PMID 12948274 from Journal of the Medical Association of Thailand = Chotmaihet thangphaet.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
40. Aged garlic extract with supplement is associated with increase in brown adipose, decrease in white adipose tissue and predict lack of progression in coronary atherosclerosis.

RCT • 2013 • PubMed indexed study

PMID 23453866 from International journal of cardiology.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
41. Daily supplementation with aged garlic extract, but not raw garlic, protects low density lipoprotein against in vitro oxidation.

RCT • 1999 • PubMed indexed study

PMID 10217370 from Atherosclerosis.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
42. Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality.

RCT • 2012 • PubMed indexed study

PMID 22271764 from Journal of the National Cancer Institute.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
43. Aged garlic extract supplemented with B vitamins, folic acid and L-arginine retards the progression of subclinical atherosclerosis: a randomized clinical trial.

RCT • 2009 • PubMed indexed study

PMID 19573556 from Preventive medicine.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
44. Effect of raw garlic vs commercial garlic supplements on plasma lipid concentrations in adults with moderate hypercholesterolemia: a randomized clinical trial.

RCT • 2007 • PubMed indexed study

PMID 17325296 from Archives of internal medicine.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
45. Aged garlic extract improves endothelial function in men with coronary artery disease.

RCT • 2005 • PubMed indexed study

PMID 16041725 from Phytotherapy research : PTR.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
46. Changes in platelet function and susceptibility of lipoproteins to oxidation associated with administration of aged garlic extract.

RCT • 1998 • PubMed indexed study

PMID 9641475 from Journal of cardiovascular pharmacology.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
47. Effect of short-term administration of garlic supplements on single-dose ritonavir pharmacokinetics in healthy volunteers.

RCT • 2003 • PubMed indexed study

PMID 12580992 from British journal of clinical pharmacology.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
48. Factorial trial of three interventions to reduce the progression of precancerous gastric lesions in Shandong, China: design issues and initial data.

RCT • 1998 • PubMed indexed study

PMID 9683311 from Controlled clinical trials.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
49. Relation of oxidative biomarkers, vascular dysfunction, and progression of coronary artery calcium.

RCT • 2010 • PubMed indexed study

PMID 20152239 from The American journal of cardiology.

Outcome: Study design: RCT. Quality score: 7.5/10.[1322,1324,1365, etc.]

Open source
50. Dietary supplementation with aged garlic extract inhibits ADP-induced platelet aggregation in humans.

RCT • 2000 • PubMed indexed study

PMID 11053504 from The Journal of nutrition.

Outcome: Study design: CONTROLLED_TRIAL. Quality score: 7.1/10.[1322,1324,1365, etc.]

Open source
51. A factorial trial including garlic supplements assesses effect in reducing precancerous gastric lesions.

RCT • 2006 • PubMed indexed study

PMID 16484571 from The Journal of nutrition.

Outcome: Study design: CONTROLLED_TRIAL. Quality score: 7.1/10.[1322,1324,1365, etc.]

Open source
52. Effects of garlic (Allium sativum L.) supplementation on cytochrome P450 2D6 and 3A4 activity in healthy volunteers.

RCT • 2003 • PubMed indexed study

PMID 12891227 from Clinical pharmacology and therapeutics.

Outcome: Study design: CONTROLLED_TRIAL. Quality score: 6.5/10.[1322,1324,1365, etc.]

Open source
53. Sickle cell anemia: a potential nutritional approach for a molecular disease.

RCT • 2000 • PubMed indexed study

PMID 10793299 from Nutrition (Burbank, Los Angeles County, Calif.).

Outcome: Study design: CONTROLLED_TRIAL. Quality score: 6.5/10.[1322,1324,1365, etc.]

Open source
54. Protective Effect of Garlic on Cellular Senescence in UVB-Exposed HaCaT Human Keratinocytes.

COHORT • 2016 • PubMed indexed study

PMID 27483310 from Nutrients.

Outcome: Study design: COHORT. Quality score: 5.9/10.[1322,1324,1365, etc.]

Open source
55. Efficacy, side effects, adherence, affordability, and procurement of dietary supplements for treating hypercholesterolemia: a narrative review.

COHORT • 2024 • PubMed indexed study

PMID 39563466 from Journal of health, population, and nutrition.

Outcome: Study design: COHORT. Quality score: 5.8/10.[1322,1324,1365, etc.]

Open source
56. Prevalence, Beliefs, and the Practice of the Use of Herbal and Dietary Supplements Among Adults in Saudi Arabia: An Observational Study.

COHORT • 2022 • PubMed indexed study

PMID 35596542 from Inquiry : a journal of medical care organization, provision and financing.

Outcome: Study design: COHORT. Quality score: 5.7/10.[1322,1324,1365, etc.]

Open source
57. Garlic: nature's protection against physiological threats.

PUBMED • 2009 • PubMed indexed study

PMID 19484634 from Critical reviews in food science and nutrition.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.5/10.[1322,1324,1365, etc.]

Open source
58. Mechanism of Action and Interaction of Garlic Extract and Established Therapeutics in Prostate Cancer.

PUBMED • 2025 • PubMed indexed study

PMID 40004239 from International journal of molecular sciences.

Outcome: Study design: OTHER. Quality score: 5.3/10.[1322,1324,1365, etc.]

Open source
59. Dual protection of aqueous garlic extract biomolecules against hemolysis and its oxidation products in preventing inflammation.

PUBMED • 2024 • PubMed indexed study

PMID 39097898 from Cellular and molecular biology (Noisy-le-Grand, France).

Outcome: Study design: OTHER. Quality score: 5.3/10.[1322,1324,1365, etc.]

Open source
60. Garlic and Heart Disease.

PUBMED • 2016 • PubMed indexed study

PMID 26764327 from The Journal of nutrition.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.2/10.[1322,1324,1365, etc.]

Open source
61. Nutraceuticals and Blood Pressure Control: Results from Clinical Trials and Meta-Analyses.

PUBMED • 2015 • PubMed indexed study

PMID 25788027 from High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.2/10.[1322,1324,1365, etc.]

Open source
62. Intake of garlic and its bioactive components.

PUBMED • 2001 • PubMed indexed study

PMID 11238796 from The Journal of nutrition.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]

Open source
63. Cholesterol-lowering effect of garlic extracts and organosulfur compounds: human and animal studies.

PUBMED • 2001 • PubMed indexed study

PMID 11238803 from The Journal of nutrition.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]

Open source
64. Evidence of clinically relevant efficacy for dietary supplements and nutraceuticals.

PUBMED • 2013 • PubMed indexed study

PMID 23430658 from Current hypertension reports.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]

Open source
65. Historical perspective on garlic and cardiovascular disease.

PUBMED • 2001 • PubMed indexed study

PMID 11238800 from The Journal of nutrition.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]

Open source
66. Protection against Helicobacter pylori and other bacterial infections by garlic.

PUBMED • 2001 • PubMed indexed study

PMID 11238826 from The Journal of nutrition.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1322,1324,1365, etc.]

Open source
67. A Paradoxical Vasodilatory Nutraceutical Intervention for Prevention and Attenuation of Migraine-A Hypothetical Review.

PUBMED • 2020 • PubMed indexed study

PMID 32824835 from Nutrients.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.0/10.[1322,1324,1365, etc.]

Open source
68. Anti-cancer activities of S-allylmercaptocysteine from aged garlic.

PUBMED • 2019 • PubMed indexed study

PMID 30704623 from Chinese journal of natural medicines.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.7/10.[1322,1324,1365, etc.]

Open source
69. The Emerging Role of Nutraceuticals and Phytochemicals in the Prevention and Treatment of Alzheimer's Disease.

PUBMED • 2020 • PubMed indexed study

PMID 32651325 from Journal of Alzheimer's disease : JAD.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.7/10.[1322,1324,1365, etc.]

Open source
70. Effects of aged garlic extract and FruArg on gene expression and signaling pathways in lipopolysaccharide-activated microglial cells.

PUBMED • 2016 • PubMed indexed study

PMID 27734935 from Scientific reports.

Outcome: Study design: OTHER. Quality score: 4.7/10.[1322,1324,1365, etc.]

Open source
71. The Role of Adiponectin in Cardiometabolic Diseases: Effects of Nutritional Interventions.

PUBMED • 2016 • PubMed indexed study

PMID 26764331 from The Journal of nutrition.

Outcome: Study design: OTHER. Quality score: 4.7/10.[1322,1324,1365, etc.]

Open source
72. Nutraceuticals for blood pressure control.

PUBMED • 2015 • PubMed indexed study

PMID 26362125 from Annals of medicine.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.6/10.[1322,1324,1365, etc.]

Open source
73. Composition, stability, and bioavailability of garlic products used in a clinical trial.

PUBMED • 2005 • PubMed indexed study

PMID 16076102 from Journal of agricultural and food chemistry.

Outcome: Study design: OTHER. Quality score: 4.6/10.[1322,1324,1365, etc.]

Open source
74. Effects of garlic extract consumption on blood lipid and oxidant/antioxidant parameters in humans with high blood cholesterol.

PUBMED • 2004 • PubMed indexed study

PMID 15157944 from The Journal of nutritional biochemistry.

Outcome: Study design: OTHER. Quality score: 4.6/10.[1322,1324,1365, etc.]

Open source
75. The effects of garlic preparations against human tumor cell proliferation.

PUBMED • 1999 • PubMed indexed study

PMID 10228605 from Phytomedicine : international journal of phytotherapy and phytopharmacology.

Outcome: Study design: OTHER. Quality score: 4.6/10.[1322,1324,1365, etc.]

Open source
76. Dietary supplementation with aged garlic extract reduces plasma and urine concentrations of 8-iso-prostaglandin F(2 alpha) in smoking and nonsmoking men and women.

PUBMED • 2002 • PubMed indexed study

PMID 11823573 from The Journal of nutrition.

Outcome: Study design: OTHER. Quality score: 4.6/10.[1322,1324,1365, etc.]

Open source
77. Health benefits of herbs and spices: the past, the present, the future.

PUBMED • 2006 • PubMed indexed study

PMID 17022438 from The Medical journal of Australia.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1322,1324,1365, etc.]

Open source
78. [Antifungal effect in selected natural compounds and probiotics and their possible use in prophylaxis of vulvovaginitis].

PUBMED • 2005 • PubMed indexed study

PMID 16180802 from Ceska gynekologie.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1322,1324,1365, etc.]

Open source
79. [New pharmacological activities of garlic and its constituents].

PUBMED • 1997 • PubMed indexed study

PMID 9503413 from Nihon yakurigaku zasshi. Folia pharmacologica Japonica.

Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.5/10.[1322,1324,1365, etc.]

Open source
80. Aged garlic extract enhances heme oxygenase-1 and glutamate-cysteine ligase modifier subunit expression via the nuclear factor erythroid 2-related factor 2-antioxidant response element signaling pathway in human endothelial cells.

PUBMED • 2016 • PubMed indexed study

PMID 26507778 from Nutrition research (New York, N.Y.).

Outcome: Study design: OTHER. Quality score: 4.4/10.[1322,1324,1365, etc.]

Open source
81. Investigation of taurine and aqueous garlic extract diet supplementation effect on the healing of rat osteoporotic fractures.

ANIMAL • 2023 • PubMed indexed study

PMID 36945935 from Turkish journal of medical sciences.

Outcome: Study design: ANIMAL. Quality score: 4.3/10.[1322,1324,1365, etc.]

Open source
82. Attenuation of chronic tension headache frequency and severity with daily L-arginine and aged garlic extract dietary supplementation.

MECHANISTIC • 2022 • PubMed indexed study

PMID 34302129 from European journal of clinical nutrition.

Outcome: Study design: CASE_REPORT. Quality score: 4.3/10.[1322,1324,1365, etc.]

Open source
83. Resolution of non-psychogenic epileptic-like seizures utilizing a vasodilatory and anti-inflammatory dietary intervention.

MECHANISTIC • 2016 • PubMed indexed study

PMID 27245208 from European journal of clinical nutrition.

Outcome: Study design: CASE_REPORT. Quality score: 4.2/10.[1322,1324,1365, etc.]

Open source
84. Protective Effects of AGE and Its Components on Neuroinflammation and Neurodegeneration.

PUBMED • 2016 • PubMed indexed study

PMID 27263111 from Neuromolecular medicine.

Outcome: Study design: OTHER. Quality score: 4.1/10.[1322,1324,1365, etc.]

Open source
85. Garlic extract in bladder cancer prevention: Evidence from T24 bladder cancer cell xenograft model, tissue microarray, and gene network analysis.

PUBMED • 2017 • PubMed indexed study

PMID 28498422 from International journal of oncology.

Outcome: Study design: OTHER. Quality score: 4.1/10.[1322,1324,1365, etc.]

Open source
86. Dehydrodiconiferyl alcohol suppresses monocyte adhesion to endothelial cells by attenuation of JNK signaling pathway.

PUBMED • 2015 • PubMed indexed study

PMID 26271597 from Biochemical and biophysical research communications.

Outcome: Study design: OTHER. Quality score: 4.1/10.[1322,1324,1365, etc.]

Open source
87. HIV protease inhibitors: garlic supplements and first-pass intestinal metabolism impact on the therapeutic efficacy.

PUBMED • 2010 • PubMed indexed study

PMID 21104925 from Biopharmaceutics & drug disposition.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
88. Garlic flavonoids and organosulfur compounds: impact on the hepatic pharmacokinetics of saquinavir and darunavir.

PUBMED • 2010 • PubMed indexed study

PMID 20930421 from Drug metabolism and pharmacokinetics.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
89. Inhibitory effect of whole strawberries, garlic juice or kale juice on endogenous formation of N-nitrosodimethylamine in humans.

PUBMED • 2002 • PubMed indexed study

PMID 12175517 from Cancer letters.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
90. The mechanisms responsible for garlic - drug interactions and their in vivo relevance.

PUBMED • 2013 • PubMed indexed study

PMID 21838705 from Current drug metabolism.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
91. Urinary excretion of N-acetyl-S-allyl-L-cysteine upon garlic consumption by human volunteers.

PUBMED • 1996 • PubMed indexed study

PMID 8870956 from Archives of toxicology.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
92. Testing garlic for possible anti-ageing effects on long-term growth characteristics, morphology and macromolecular synthesis of human fibroblasts in culture.

PUBMED • 1994 • PubMed indexed study

PMID 7526077 from Journal of ethnopharmacology.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
93. Aged garlic extract restores nitric oxide bioavailability in cultured human endothelial cells even under conditions of homocysteine elevation.

PUBMED • 2013 • PubMed indexed study

PMID 23127645 from Journal of ethnopharmacology.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
94. Kyolic and Pycnogenol increase human growth hormone secretion in genetically-engineered keratinocytes.

PUBMED • 2002 • PubMed indexed study

PMID 12127300 from Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
95. A gas chromatography-mass spectrometry method for the quantitation of N-nitrosoproline and N-acetyl-S-allylcysteine in human urine: application to a study of the effects of garlic consumption on nitrosation.

PUBMED • 2009 • PubMed indexed study

PMID 19643074 from Analytical biochemistry.

Outcome: Study design: OTHER. Quality score: 4.0/10.[1322,1324,1365, etc.]

Open source
96. Garlic inhibits microsomal triglyceride transfer protein gene expression in human liver and intestinal cell lines and in rat intestine.

ANIMAL • 2002 • PubMed indexed study

PMID 12042427 from The Journal of nutrition.

Outcome: Study design: ANIMAL. Quality score: 3.6/10.[1322,1324,1365, etc.]

Open source
97. In vitro interactions between aged garlic extract and drugs used for the treatment of cardiovascular and diabetic patients.

IN_VITRO • 2010 • PubMed indexed study

PMID 20140680 from European journal of nutrition.

Outcome: Study design: IN_VITRO. Quality score: 3.1/10.[1322,1324,1365, etc.]

Open source
98. In vitro effects of aged garlic extract and other nutritional supplements on sickle erythrocytes.

IN_VITRO • 2001 • PubMed indexed study

PMID 11238822 from The Journal of nutrition.

Outcome: Study design: IN_VITRO. Quality score: 3.1/10.[1322,1324,1365, etc.]

Open source
99. The influence of aged garlic extract on the uptake of saquinavir and darunavir into HepG2 cells and rat liver slices.

ANIMAL • 2010 • PubMed indexed study

PMID 20610890 from Drug metabolism and pharmacokinetics.

Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1322,1324,1365, etc.]

Open source
100. Renoprotective effect of aged garlic extract in streptozotocin-induced diabetic rats.

ANIMAL • 2013 • PubMed indexed study

PMID 23543654 from Indian journal of pharmacology.

Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1322,1324,1365, etc.]

Open source
101. Effect of allicin from garlic powder on serum lipids and blood pressure in rats fed with a high cholesterol diet.

ANIMAL • 2000 • PubMed indexed study

PMID 10882191 from Prostaglandins, leukotrienes, and essential fatty acids.

Outcome: Study design: ANIMAL. Quality score: 3.0/10.[1322,1324,1365, etc.]

Open source
102. In Vitro, In Vivo, and In Silico Investigation of Synbiotic-Mediated Activation of PPAR-α Curtails Nonalcoholic Steatohepatitis (NASH) in Wistar Rats by Inhibiting PNPLA3/SREBP1-c Lead Inflammatory Injury of Hepatic Cells.

IN_VITRO • 2025 • PubMed indexed study

PMID 40017524 from Mediators of inflammation.

Outcome: Study design: IN_VITRO. Quality score: 2.8/10.[1322,1324,1365, etc.]

Open source
103. Helicobacter pylori--in vitro susceptibility to garlic (Allium sativum) extract.

IN_VITRO • 1997 • PubMed indexed study

PMID 9121937 from Nutrition and cancer.

Outcome: Study design: IN_VITRO. Quality score: 2.5/10.[1322,1324,1365, etc.]

Open source
104. Transwell-grown HepG2 cell monolayers as in vitro permeability model to study drug-drug or drug-food interactions.

IN_VITRO • 2011 • PubMed indexed study

PMID 21138349 from Journal of medicinal food.

Outcome: Study design: IN_VITRO. Quality score: 2.5/10.[1322,1324,1365, etc.]

Open source