Supplement
Contains bioactive phytochemicals that may modulate stress, immune, and metabolic pathways.[1585,2980,3424, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
86/100
High depth from human/RCT/meta counts
Community Direction
67
Positive Lean • confidence Low
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 11 • mentions 6 • links 22
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
If you are experiencing a medical emergency, call 911 or your local emergency number immediately.
Goal alignment: Stress Resilience, Mood, Immune Support, Longevity.[42,256,267, etc.]
Dose guide: Human-study daily dose: 50 mg-1000 mg/day (higher-confidence extraction from PubMed abstracts)..[42,256,267, etc.]
Category
Botanical
Evidence Tier
HIGH
Daily Guide
Human-study daily dose: 50 mg-1000 mg/day (higher-confidence extraction from PubMed abstracts).
Clinical Depth
Humans: 57 • RCTs: 11 • Meta: 0
Cohort / Real-World
Cohort signals: 0
Safety Markers
Adverse signals: 155 • Interactions: 142
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
229 total studies · 2 recent
Timeline
Animal-only studies
845
In vitro / tissue
440
Total indexed
229
Safety adverse signals
155
Interaction signals
142
Human studies
57
Weighted direction score: 67 (Positive Lean)
High when >=2 human meta-analyses, or >=5 human RCTs with substantial human literature volume.
Animal-only studies
845
In vitro / tissue
440
Total indexed
229
Safety adverse signals
155
Interaction signals
142
Human studies
57
Randomized trials
11
Meta-analyses
0
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 38580687 • 2024 Apr 5
A randomized controlled clinical trial examining the effects of Cordyceps militaris beverage on the immune response in healthy adults.
Sci Rep
Open PubMedPMID 31623349 • 2019 Oct 3
Rhodiola/Cordyceps-Based Herbal Supplement Promotes Endurance Training-Improved Body Composition But Not Oxidative Stress and Metabolic Biomarkers: A Preliminary Randomized Controlled Study.
Nutrients
Open PubMedPMID 36374982 • 2022
Efficacy of Cordyceps cicadae (Ascomycota) Mycelium Supplementation for Amelioration of Dry Eye Symptoms: A Randomized, Double-Blind Clinical Pilot Study.
Int J Med Mushrooms
Open PubMedPMID 38501161 • 2024 Apr 22
Cordyceps sinensis accelerates stem cell recruitment to human skeletal muscle after exercise.
Food Funct
Open PubMedPMID 33078636 • 2021
Effects of Concurrent Training and a Multi-Ingredient Performance Supplement Containing Rhodiola rosea and Cordyceps sinensis on Body Composition, Performance, and Health in Active Men.
J Diet Suppl
Open PubMedPMID 15118196 • 2004 Apr
Cordyceps Sinensis (CordyMax Cs-4) supplementation does not improve endurance exercise performance.
Int J Sport Nutr Exerc Metab
Open PubMedPMID 37373268 • 2023 Jun 14
Anti-Cancer Potential of Edible/Medicinal Mushrooms in Breast Cancer.
Int J Mol Sci
Open PubMedPMID 29568244 • 2018
Herbal medicine for sports: a review.
J Int Soc Sports Nutr
Open PubMedPMID 32545666 • 2020 Jun 12
Cordycepin for Health and Wellbeing: A Potent Bioactive Metabolite of an Entomopathogenic Cordyceps Medicinal Fungus and Its Nutraceutical and Therapeutic Potential.
Molecules
Open PubMedPMID 36995535 • 2023 Jun
Medicinal Mushroom Supplements in Cancer: A Systematic Review of Clinical Studies.
Curr Oncol Rep
Open PubMedPMID 35889330 • 2022 Jul 12
Medicinal Fungi with Antiviral Effect.
Molecules
Open PubMedBenefit reports: 5
Adverse reports: 1
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.28
Benefits
Adverse
No Effect
Moderate positive empirical signal; apply a light priority boost.
Reddit evidence: 3 mentions (confidence 0.28) across Supplements, Biohackers.
Amazon signal: 1 products scanned (948 ratings) (confidence 0.79).
GNC signal: 0 products scanned (confidence 0.00) [BLOCKED].
PerimeterX / captcha block encountered.
Use adverse/interactions PubMed signal counts for screening; perform clinician review before high-dose or multi-drug stack use.
Lowest observed monthly cost signal: $89.99 (FlavCity Chocolate Protein Powder, Organic Cocoa with Collagen Peptides, Reishi & Cordyceps Mushrooms - Focus, Skin, Hair & Joint Support - 100% Grass Fed Whey All in One Smoothie, 20 Servings).
Human-study daily dose signal: 50 mg-1000 mg/day (confidence HIGH).
Extracted from 4 dosing mentions across 3 PubMed studies (mg/day).
Imported legacy community score: 8.0/10 (heuristic mapping confidence 1.00).
Imported legacy monthly cost signal: ~$25.00.
Legacy community note: Highly regarded among athletes and biohackers. Users report noticeable energy boost and better endurance without jitteriness. Popular pre-workout ingredient.
Sentiment Score
0.82322/100
Benefit Mentions
Adverse Mentions
No adverse mentions recorded.
Best Responders
No responder profile recorded.
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Open mentionpost • r/Biohackers • benefit
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Open mentionamazon
FlavCity Chocolate Protein Powder, Organic Cocoa with Collagen Peptides, Reishi & Cordyceps Mushrooms - Focus, Skin, Hair & Joint Support - 100% Grass Fed Whey All in One Smoothie, 20 Servings
Rating: 4.2 | Reviews: 948
Open productEvidence Sources
Community Sources
PUBMED • Humans + preclinical triage
Counts aggregated from automated literature sweep and tiering rules.
Outcome: Tier HIGH; humans 57, RCTs 11, meta-analyses 0.[1585,2980,3424, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38580687 from Sci Rep.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31623349 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 36374982 from Int J Med Mushrooms.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38501161 from Food Funct.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33078636 from J Diet Suppl.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2004 • Human evidence curation set
PMID 15118196 from Int J Sport Nutr Exerc Metab.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37373268 from Int J Mol Sci.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29568244 from J Int Soc Sports Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32545666 from Molecules.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36995535 from Curr Oncol Rep.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35889330 from Molecules.
Outcome: See linked PubMed abstract for methods and outcomes.[1585,2980,3424, etc.]
Open source