Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
34
Positive Lean • confidence Low
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 24 • mentions 8 • links 214
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
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Effect of combination of Beta Glucan and Lactobacillus rhamnosus HerizI on white blood cell counts and serum levels of IL-4 and IL-12 in women with breast cancer undergoing chemotherapy: A randomized double-blind placebo-controlled clinical trial.
Effect of a polysaccharide-rich hydrolysate from Saccharomyces cerevisiae (LipiGo®) in body weight loss: randomised, double-blind, placebo-controlled clinical trial in overweight and obese adults.
Efficacy of yeast beta-glucan 1,3/1,6 supplementation on respiratory infection, fatigue, immune markers and gut health among moderate stress adults in Klang Valley of Malaysia: protocol for a randomised, double-blinded, placebo-controlled, parallel-group study.
Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
Yeast (1,3)-(1,6)-beta-glucan helps to maintain the body's defence against pathogens: a double-blind, randomized, placebo-controlled, multicentric study in healthy subjects.
Effect of oat supplementation interventions on cardiovascular disease risk markers: a systematic review and meta-analysis of randomized controlled trials.
Impact of non-digestible carbohydrates and prebiotics on immunity, infections, inflammation and vaccine responses: a systematic review of evidence in healthy humans and a discussion of mechanistic proposals.
The effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: a systematic review and meta-analysis of randomised-controlled trials.
A systematic review and meta-analysis of randomized controlled trials of the effect of barley β-glucan on LDL-C, non-HDL-C and apoB for cardiovascular disease risk reduction(i-iv).
Effects of Oat Beta-Glucan Intake on Lipid Profiles in Hypercholesterolemic Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects.
Effect of beta glucan on white blood cell counts and serum levels of IL-4 and IL-12 in women with breast cancer undergoing chemotherapy: a randomized double-blind placebo-controlled clinical trial.
Asian Pacific journal of cancer prevention : APJCP
Effect of high beta-glucan barley on serum cholesterol concentrations and visceral fat area in Japanese men--a randomized, double-blinded, placebo-controlled trial.
Plant foods for human nutrition (Dordrecht, Netherlands)
Yeast-derived (Wellmune) for immune support, oat-derived for cholesterol. Two different products with different mechanisms. | Step2: Moderate positive empirical signal; apply a light priority boost.
Reddit evidence: 2 mentions (confidence 0.22) across Biohackers, Supplements.
Organic Mushrooms Lion’s Mane – 90% fruiting body + 10% mycelium (erinacine A quantified). Does this make sense chemically? I’ve been comparing Lion’s Mane supplements and wanted a sanity check from people who understand extraction chemist…
What do you think of my stack ? 🧬 supermonkeygodkingemperor's Master Alzheimer's Reversal Protocol 4.0 *(Building on Neuro-Resilience Stack 3.0: Shifting from prevention to active reversal via enhanced neurogenesis, amyloid/tau clearance,…
Best Psyllium Husk Supplement in the UK? Or Safer Alternatives if Lead Levels Are Unclear? Hi everyone, I've been trying to up my fibre intake for heart health and cholesterol management, and psyllium husk keeps coming up as one of the bes…
Open source 5. A systematic review and meta-analysis of beta-glucan consumption on glycemic control in hypercholesterolemic individuals.
PUBMED • 2015 • Human evidence curation set
PMID 26001090 from International journal of food sciences and nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 6. Adaptogenic Effects of Mushroom Blend Supplementation on Stress, Fatigue, and Sleep: A Randomised, Double-Blind, and Placebo-Controlled Trial.
PUBMED • 2026 • Human evidence curation set
PMID 41540766 from Brain and behavior.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 7. Effect of combination of Beta Glucan and Lactobacillus rhamnosus HerizI on white blood cell counts and serum levels of IL-4 and IL-12 in women with breast cancer undergoing chemotherapy: A randomized double-blind placebo-controlled clinical trial.
PUBMED • 2024 • Human evidence curation set
PMID 38777445 from Clinical nutrition ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 8. Effect of a polysaccharide-rich hydrolysate from Saccharomyces cerevisiae (LipiGo®) in body weight loss: randomised, double-blind, placebo-controlled clinical trial in overweight and obese adults.
PUBMED • 2017 • Human evidence curation set
PMID 28251654 from Journal of the science of food and agriculture.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 9. Efficacy of yeast beta-glucan 1,3/1,6 supplementation on respiratory infection, fatigue, immune markers and gut health among moderate stress adults in Klang Valley of Malaysia: protocol for a randomised, double-blinded, placebo-controlled, parallel-group study.
PUBMED • 2025 • Human evidence curation set
PMID 39832981 from BMJ open.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 10. The separate effects of whole oats and isolated beta-glucan on lipid profile: A systematic review and meta-analysis of randomized controlled trials.
PUBMED • 2023 • Human evidence curation set
PMID 36657917 from Clinical nutrition ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 11. Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial.
PUBMED • 2023 • Human evidence curation set
PMID 37960157 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 12. Yeast Beta-Glucan Enhances Antibody Response Following Influenza Vaccination - A Double-Blind, Randomized, Placebo-Controlled Pilot Trial.
PUBMED • 2025 • Human evidence curation set
PMID 40746014 from Journal of dietary supplements.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 13. Yeast (1,3)-(1,6)-beta-glucan helps to maintain the body's defence against pathogens: a double-blind, randomized, placebo-controlled, multicentric study in healthy subjects.
PUBMED • 2013 • Human evidence curation set
PMID 23340963 from European journal of nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 14. Effect of oat supplementation interventions on cardiovascular disease risk markers: a systematic review and meta-analysis of randomized controlled trials.
PUBMED • 2022 • Human evidence curation set
PMID 34977959 from European journal of nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 15. Effect of a Euglena gracilis Fermentate on Immune Function in Healthy, Active Adults: A Randomized, Double-Blind, Placebo-Controlled Trial.
PUBMED • 2019 • Human evidence curation set
PMID 31816842 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 16. Impact of non-digestible carbohydrates and prebiotics on immunity, infections, inflammation and vaccine responses: a systematic review of evidence in healthy humans and a discussion of mechanistic proposals.
PUBMED • 2026 • Human evidence curation set
PMID 40516031 from Critical reviews in food science and nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 17. The effect of oat β-glucan on LDL-cholesterol, non-HDL-cholesterol and apoB for CVD risk reduction: a systematic review and meta-analysis of randomised-controlled trials.
PUBMED • 2016 • Human evidence curation set
PMID 27724985 from The British journal of nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 18. Effects of dietary fibre type on blood pressure: a systematic review and meta-analysis of randomized controlled trials of healthy individuals.
PUBMED • 2015 • Human evidence curation set
PMID 25668347 from Journal of hypertension.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 19. A systematic review and meta-analysis of randomized controlled trials of the effect of barley β-glucan on LDL-C, non-HDL-C and apoB for cardiovascular disease risk reduction(i-iv).
PUBMED • 2016 • Human evidence curation set
PMID 27273067 from European journal of clinical nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 20. Effects of Oat Beta-Glucan Intake on Lipid Profiles in Hypercholesterolemic Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
PUBMED • 2022 • Human evidence curation set
PMID 35631184 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 21. Soluble and Insoluble Yeast β-Glucan Differentially Affect Upper Respiratory Tract Infection in Marathon Runners: A Double-Blind, Randomized Placebo-Controlled Trial.
PUBMED • 2020 • Human evidence curation set
PMID 31573387 from Journal of medicinal food.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 22. Effects of Yeast (1,3)-(1,6)-Beta-Glucan on Severity of Upper Respiratory Tract Infections: A Double-Blind, Randomized, Placebo-Controlled Study in Healthy Subjects.
PUBMED • 2019 • Human evidence curation set
PMID 30198828 from Journal of the American College of Nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 23. Galactomannans are the most effective soluble dietary fibers in type 2 diabetes: a systematic review and network meta-analysis.
PUBMED • 2023 • Human evidence curation set
PMID 36811560 from The American journal of clinical nutrition.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 24. The Metabolic Effects of Oats Intake in Patients with Type 2 Diabetes: A Systematic Review and Meta-Analysis.
PUBMED • 2015 • Human evidence curation set
PMID 26690472 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 25. Effect of Oat β-Glucan Intake on Glycaemic Control and Insulin Sensitivity of Diabetic Patients: A Meta-Analysis of Randomized Controlled Trials.
PUBMED • 2016 • Human evidence curation set
PMID 26771637 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 26. Effect of beta glucan on white blood cell counts and serum levels of IL-4 and IL-12 in women with breast cancer undergoing chemotherapy: a randomized double-blind placebo-controlled clinical trial.
PUBMED • 2014 • Human evidence curation set
PMID 25081694 from Asian Pacific journal of cancer prevention : APJCP.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 27. Effect of Oat Consumption on Blood Pressure: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
PUBMED • 2023 • Human evidence curation set
PMID 36435335 from Journal of the Academy of Nutrition and Dietetics.
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 28. Effect of high beta-glucan barley on serum cholesterol concentrations and visceral fat area in Japanese men--a randomized, double-blinded, placebo-controlled trial.
PUBMED • 2008 • Human evidence curation set
PMID 18074229 from Plant foods for human nutrition (Dordrecht, Netherlands).
Outcome: See linked PubMed abstract for methods and outcomes.[1320,1361,1376, etc.]
Open source 29. Effects of cereal beta-glucan consumption on body weight, body mass index, waist circumference and total energy intake: A meta-analysis of randomized controlled trials.
META_ANALYSIS • 2019 • PubMed indexed study
PMID 30935520 from Complementary therapies in medicine.
Outcome: Study design: META_ANALYSIS. Quality score: 9.2/10.[1320,1361,1376, etc.]
Open source 30. Effects of cereal fibers on short-chain fatty acids in healthy subjects and patients: a meta-analysis of randomized clinical trials.
META_ANALYSIS • 2021 • PubMed indexed study
PMID 34152334 from Food & function.
Outcome: Study design: META_ANALYSIS. Quality score: 9.2/10.[1320,1361,1376, etc.]
Open source 31. Supplementation with a β-glucan tablet has no effect on hyperlipidemia: a randomized, placebo-controlled clinical trial.
RCT • 2023 • PubMed indexed study
PMID 37054888 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 9.2/10.[1320,1361,1376, etc.]
Open source 32. The effect of viscous soluble fiber on blood pressure: A systematic review and meta-analysis of randomized controlled trials.
META_ANALYSIS • 2018 • PubMed indexed study
PMID 29153856 from Nutrition, metabolism, and cardiovascular diseases : NMCD.
Outcome: Study design: META_ANALYSIS. Quality score: 9.1/10.[1320,1361,1376, etc.]
Open source 33. The difference between oats and beta-glucan extract intake in the management of HbA1c, fasting glucose and insulin sensitivity: a meta-analysis of randomized controlled trials.
META_ANALYSIS • 2016 • PubMed indexed study
PMID 26840185 from Food & function.
Outcome: Study design: META_ANALYSIS. Quality score: 9.1/10.[1320,1361,1376, etc.]
Open source 34. Increasing oat β-glucan viscosity in a breakfast meal slows gastric emptying and reduces glycemic and insulinemic responses but has no effect on appetite, food intake, or plasma ghrelin and PYY responses in healthy humans: a randomized, placebo-controlled, crossover trial.
RCT • 2020 • PubMed indexed study
PMID 31828287 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 9.1/10.[1320,1361,1376, etc.]
Open source 35. Synbiotic control of inflammation and infection in severe acute pancreatitis: a prospective, randomized, double blind study.
RCT • 2007 • PubMed indexed study
PMID 17523328 from Hepato-gastroenterology.
Outcome: Study design: RCT. Quality score: 9.1/10.[1320,1361,1376, etc.]
Open source 36. Impact of Dietary Supplements on Clinical Outcomes and Quality of Life in Patients with Breast Cancer: A Systematic Review.
SYSTEMATIC_REVIEW • 2025 • PubMed indexed study
PMID 40290044 from Nutrients.
Outcome: Study design: SYSTEMATIC_REVIEW. Quality score: 9.1/10.[1320,1361,1376, etc.]
Open source 37. Meta-analysis of the effect of β-glucan intake on blood cholesterol and glucose levels.
META_ANALYSIS • 2011 • PubMed indexed study
PMID 21470820 from Nutrition (Burbank, Los Angeles County, Calif.).
Outcome: Study design: META_ANALYSIS. Quality score: 9.0/10.[1320,1361,1376, etc.]
Open source 38. The effects of waxy barley on defecation, sleep, mental health, and quality of life: a randomized double-blind parallel-group comparison study.
RCT • 2025 • PubMed indexed study
PMID 40336123 from Journal of physiological anthropology.
Outcome: Study design: RCT. Quality score: 8.8/10.[1320,1361,1376, etc.]
Open source 39. A randomized Placebo-Controlled Clinical Trial to Evaluate the Medium-Term Effects of Oat Fibers on Human Health: The Beta-Glucan Effects on Lipid Profile, Glycemia and inTestinal Health (BELT) Study.
RCT • 2020 • PubMed indexed study
PMID 32138344 from Nutrients.
Outcome: Study design: RCT. Quality score: 8.8/10.[1320,1361,1376, etc.]
Open source 40. Effects of Dietary Fibres on Acute Indomethacin-Induced Intestinal Hyperpermeability in the Elderly: A Randomised Placebo Controlled Parallel Clinical Trial.
RCT • 2020 • PubMed indexed study
PMID 32629992 from Nutrients.
Outcome: Study design: RCT. Quality score: 8.8/10.[1320,1361,1376, etc.]
Open source 41. Six Weeks of Baker's Yeast β-Glucan Supplementation Reveals Unique Immune Maturation mRNA Signature: Implications for Immunity?
RCT • 2026 • PubMed indexed study
PMID 41596240 from International journal of molecular sciences.
Outcome: Study design: RCT. Quality score: 8.8/10.[1320,1361,1376, etc.]
Open source 42. Effect of Oat (Avena sativa L.) Consumption on Lipid Profile With Focus on Triglycerides and High-density Lipoprotein Cholesterol (HDL-C): An Updated Systematic Review.
SYSTEMATIC_REVIEW • 2023 • PubMed indexed study
PMID 35192870 from Current problems in cardiology.
Outcome: Study design: SYSTEMATIC_REVIEW. Quality score: 8.8/10.[1320,1361,1376, etc.]
Open source 43. Novel nutraceutical supplements with yeast β-glucan, prebiotics, minerals, and Silybum marianum (silymarin) ameliorate obesity-related metabolic and clinical parameters: A double-blind randomized trial.
RCT • 2022 • PubMed indexed study
PMID 36778595 from Frontiers in endocrinology.
Outcome: Study design: RCT. Quality score: 8.7/10.[1320,1361,1376, etc.]
Open source 44. A randomised controlled trial of a probiotic and a prebiotic examining metabolic and mental health outcomes in adults with pre-diabetes.
RCT • 2022 • PubMed indexed study
PMID 35332040 from BMJ open.
Outcome: Study design: RCT. Quality score: 8.7/10.[1320,1361,1376, etc.]
Open source 45. Acute effect of oat β-glucan on the bioavailability of orange juice flavanones.
RCT • 2022 • PubMed indexed study
PMID 34933644 from International journal of food sciences and nutrition.
Outcome: Study design: RCT. Quality score: 8.7/10.[1320,1361,1376, etc.]
Open source 46. Sixteen-week multicentre randomised controlled trial to study the effect of the consumption of an oat beta-glucan-enriched bread versus a whole-grain wheat bread on glycaemic control among persons with pre-diabetes: a study protocol of the CarbHealth study.
RCT • 2022 • PubMed indexed study
PMID 35998955 from BMJ open.
Outcome: Study design: RCT. Quality score: 8.7/10.[1320,1361,1376, etc.]
Open source 47. Beta-glucan, inositol and digestive enzymes improve quality of life of patients with inflammatory bowel disease and irritable bowel syndrome.
RCT • 2017 • PubMed indexed study
PMID 28724171 from European review for medical and pharmacological sciences.
Outcome: Study design: RCT. Quality score: 8.6/10.[1320,1361,1376, etc.]
Open source 48. Effects of high β-glucan barley on visceral fat obesity in Japanese individuals: A randomized, double-blind study.
RCT • 2017 • PubMed indexed study
PMID 28870472 from Nutrition (Burbank, Los Angeles County, Calif.).
Outcome: Study design: RCT. Quality score: 8.6/10.[1320,1361,1376, etc.]
Open source 49. Beta-glucan, immune function, and upper respiratory tract infections in athletes.
RCT • 2008 • PubMed indexed study
PMID 18614945 from Medicine and science in sports and exercise.
Outcome: Study design: RCT. Quality score: 8.5/10.[1320,1361,1376, etc.]
Open source 50. [Combination of early nasojejunal feeding with modern synbiotic therapy in the treatment of severe acute pancreatitis (prospective, randomized, double-blind study)].
RCT • 2005 • PubMed indexed study
PMID 16167471 from Magyar sebeszet.
Outcome: Study design: RCT. Quality score: 8.5/10.[1320,1361,1376, etc.]
Open source 51. The effect of fiber on satiety and food intake: a systematic review.
SYSTEMATIC_REVIEW • 2013 • PubMed indexed study
PMID 23885994 from Journal of the American College of Nutrition.
Outcome: Study design: SYSTEMATIC_REVIEW. Quality score: 8.5/10.[1320,1361,1376, etc.]
Open source 52. Food 4 Health - He Oranga Kai: Assessing the efficacy, acceptability and economic implications of Lactobacillus rhamnosus HN001 and β-glucan to improve glycated haemoglobin, metabolic health, and general well-being in adults with pre-diabetes: study protocol for a 2 × 2 factorial design, parallel group, placebo-controlled randomized controlled trial, with embedded qualitative study and economic analysis.
RCT • 2019 • PubMed indexed study
PMID 31358022 from Trials.
Outcome: Study design: RCT. Quality score: 8.5/10.[1320,1361,1376, etc.]
Open source 53. Effectiveness of regular oat β-glucan-enriched bread compared with whole-grain wheat bread on long-term glycemic control in adults at risk of type 2 diabetes: a randomized controlled trial.
RCT • 2025 • PubMed indexed study
PMID 40571100 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.4/10.[1320,1361,1376, etc.]
Open source 54. Beneficial effects of pleuran on asthma control and respiratory tract-infection frequency in children with perennial asthma.
RCT • 2025 • PubMed indexed study
PMID 40021713 from Scientific reports.
Outcome: Study design: RCT. Quality score: 8.4/10.[1320,1361,1376, etc.]
Open source 55. Nutraceutical composition (yeast β-glucan, prebiotics, minerals, and silymarin) predicts improvement of sleep quality and metabolic parameters: A randomized pilot study.
RCT • 2024 • PubMed indexed study
PMID 39012843 from Clinical nutrition ESPEN.
Outcome: Study design: RCT. Quality score: 8.4/10.[1320,1361,1376, etc.]
Open source 56. High molecular weight oat β-glucan enhances lipid-lowering effects of phytosterols. A randomised controlled trial.
RCT • 2020 • PubMed indexed study
PMID 30792143 from Clinical nutrition (Edinburgh, Scotland).
Outcome: Study design: RCT. Quality score: 8.3/10.[1320,1361,1376, etc.]
Open source 57. Supplementation with a soluble β-glucan exported from Shiitake medicinal mushroom, Lentinus edodes (Berk.) singer mycelium: a crossover, placebo-controlled study in healthy elderly.
RCT • 2011 • PubMed indexed study
PMID 22164761 from International journal of medicinal mushrooms.
Outcome: Study design: RCT. Quality score: 8.3/10.[1320,1361,1376, etc.]
Open source 58. Modulation of human intestinal microbiota in a clinical trial by consumption of a β-D-glucan-enriched extract obtained from Lentinula edodes.
RCT • 2021 • PubMed indexed study
PMID 33580297 from European journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.3/10.[1320,1361,1376, etc.]
Open source 59. Gastrointestinal microbiome modulator improves glucose tolerance in overweight and obese subjects: A randomized controlled pilot trial.
RCT • 2015 • PubMed indexed study
PMID 26424589 from Journal of diabetes and its complications.
Outcome: Study design: RCT. Quality score: 8.2/10.[1320,1361,1376, etc.]
Open source 60. Similar metabolic responses in pigs and humans to breads with different contents and compositions of dietary fibers: a metabolomics study.
RCT • 2014 • PubMed indexed study
PMID 24477039 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.2/10.[1320,1361,1376, etc.]
Open source 61. The impact of soluble dietary fibre on gastric emptying, postprandial blood glucose and insulin in patients with type 2 diabetes.
RCT • 2014 • PubMed indexed study
PMID 24901089 from Asia Pacific journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.2/10.[1320,1361,1376, etc.]
Open source 62. Effects of concentrated arabinoxylan and β-glucan compared with refined wheat and whole grain rye on glucose and appetite in subjects with the metabolic syndrome: a randomized study.
RCT • 2014 • PubMed indexed study
PMID 24253758 from European journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.2/10.[1320,1361,1376, etc.]
Open source 63. Efficacy of Food Industry By-Product β-Glucan/Chitin-Chitosan on Lipid Profile of Overweight and Obese Individuals: Sustainability and Nutraceuticals.
RCT • 2024 • PubMed indexed study
PMID 39408385 from Nutrients.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 64. Dietary Supplements Containing Oat Beta-Glucan and/or Green Coffee (Poly)phenols Showed Limited Effect in Modulating Cardiometabolic Risk Biomarkers in Overweight/Obese Patients without a Lifestyle Intervention.
RCT • 2023 • PubMed indexed study
PMID 37432380 from Nutrients.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 65. Oat beta-glucan supplementation does not enhance the effectiveness of an energy-restricted diet in overweight women.
RCT • 2010 • PubMed indexed study
PMID 19930764 from The British journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 66. No effect of added beta-glucan or of fructooligosaccharide on appetite or energy intake.
RCT • 2009 • PubMed indexed study
PMID 19056555 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 67. Baker's yeast β-glucan supplementation increases monocytes and cytokines post-exercise: implications for infection risk?
RCT • 2013 • PubMed indexed study
PMID 22575076 from The British journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 68. Simultaneous intake of beta-glucan and plant stanol esters affects lipid metabolism in slightly hypercholesterolemic subjects.
RCT • 2007 • PubMed indexed study
PMID 17311944 from The Journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 69. Supplementation of a high-carbohydrate breakfast with barley beta-glucan improves postprandial glycaemic response for meals but not beverages.
RCT • 2007 • PubMed indexed study
PMID 17215176 from Asia Pacific journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 70. Effects of Chronic Barley Consumption on Upper Respiratory Tract Symptoms in Japanese Healthy Adults: A Randomized, Parallel-Group, Controlled Trial.
RCT • 2024 • PubMed indexed study
PMID 39064742 from Nutrients.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 71. Carbohydrate digestion in humans from a beta-glucan-enriched barley is reduced.
RCT • 2002 • PubMed indexed study
PMID 12221214 from The Journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 72. Fibre in beverages can enhance perceived satiety.
RCT • 2009 • PubMed indexed study
PMID 19306033 from European journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 73. Soluble fiber intake at a dose approved by the US Food and Drug Administration for a claim of health benefits: serum lipid risk factors for cardiovascular disease assessed in a randomized controlled crossover trial.
RCT • 2002 • PubMed indexed study
PMID 11976156 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 74. Glucose and insulin responses to whole grain breakfasts varying in soluble fiber, beta-glucan: a dose response study in obese women with increased risk for insulin resistance.
RCT • 2009 • PubMed indexed study
PMID 19205780 from European journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 75. Cholesterol-lowering effect of beta-glucan from oat bran in mildly hypercholesterolemic subjects may decrease when beta-glucan is incorporated into bread and cookies.
RCT • 2003 • PubMed indexed study
PMID 12885701 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 76. Modest doses of beta-glucan do not reduce concentrations of potentially atherogenic lipoproteins.
RCT • 2000 • PubMed indexed study
PMID 10871560 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 77. Effects of oat gum on blood cholesterol levels in healthy young men.
RCT • 1995 • PubMed indexed study
PMID 7588502 from European journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 78. Barley and wheat foods: influence on plasma cholesterol concentrations in hypercholesterolemic men.
RCT • 1991 • PubMed indexed study
PMID 1850576 from The American journal of clinical nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 79. Oat consumption does not affect resting casual and ambulatory 24-h arterial blood pressure in men with high-normal blood pressure to stage I hypertension.
RCT • 2002 • PubMed indexed study
PMID 11880561 from The Journal of nutrition.
Outcome: Study design: RCT. Quality score: 8.1/10.[1320,1361,1376, etc.]
Open source 80. Yeast Beta-Glucan Supplementation Downregulates Markers of Systemic Inflammation after Heated Treadmill Exercise.
RCT • 2020 • PubMed indexed study
PMID 32325856 from Nutrients.
Outcome: Study design: RCT. Quality score: 8.0/10.[1320,1361,1376, etc.]
Open source 81. Beverage Containing Dispersible Yeast β-Glucan Decreases Cold/Flu Symptomatic Days After Intense Exercise: A Randomized Controlled Trial.
RCT • 2020 • PubMed indexed study
PMID 30380356 from Journal of dietary supplements.
Outcome: Study design: RCT. Quality score: 8.0/10.[1320,1361,1376, etc.]
Open source 82. Improved Glycemic Control and Variability: Application of Healthy Ingredients in Asian Staples.
RCT • 2021 • PubMed indexed study
PMID 34578981 from Nutrients.
Outcome: Study design: RCT. Quality score: 8.0/10.[1320,1361,1376, etc.]
Open source 83. Yeast β-Glucan Modulates Inflammation and Waist Circumference in Overweight and Obese Subjects.
RCT • 2017 • PubMed indexed study
PMID 27715351 from Journal of dietary supplements.
Outcome: Study design: RCT. Quality score: 7.9/10.[1320,1361,1376, etc.]
Open source 84. β-Glucan and dark chocolate: a randomized crossover study on short-term satiety and energy intake.
RCT • 2014 • PubMed indexed study
PMID 25251294 from Nutrients.
Outcome: Study design: RCT. Quality score: 7.9/10.[1320,1361,1376, etc.]
Open source 85. The role of meal viscosity and oat β-glucan characteristics in human appetite control: a randomized crossover trial.
RCT • 2014 • PubMed indexed study
PMID 24884934 from Nutrition journal.
Outcome: Study design: RCT. Quality score: 7.9/10.[1320,1361,1376, etc.]
Open source 86. A Multifunctional Bread Rich in Beta Glucans and Low in Starch Improves Metabolic Control in Type 2 Diabetes: A Controlled Trial.
RCT • 2017 • PubMed indexed study
PMID 28304350 from Nutrients.
Outcome: Study design: RCT. Quality score: 7.9/10.[1320,1361,1376, etc.]
Open source 87. Cow's milk-based beverage consumption in 1- to 4-year-olds and allergic manifestations: an RCT.
RCT • 2016 • PubMed indexed study
PMID 26920136 from Nutrition journal.
Outcome: Study design: RCT. Quality score: 7.9/10.[1320,1361,1376, etc.]
Open source 88. Effect of Consuming Oat Bran Mixed in Water before a Meal on Glycemic Responses in Healthy Humans-A Pilot Study.
RCT • 2016 • PubMed indexed study
PMID 27571099 from Nutrients.
Outcome: Study design: RCT. Quality score: 7.9/10.[1320,1361,1376, etc.]
Open source 89. Effect of oat β-glucan in managing blood pressure: a randomized cross-over pilot trial.
RCT • 2025 • PubMed indexed study
PMID 41031804 from Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
Outcome: Study design: RCT. Quality score: 7.8/10.[1320,1361,1376, etc.]
Open source 90. Benefits of Gut Microbiota Reconstitution by Beta 1,3-1,6 Glucans in Subjects with Autism Spectrum Disorder and Other Neurodegenerative Diseases.
RCT • 2023 • PubMed indexed study
PMID 36093695 from Journal of Alzheimer's disease : JAD.
Outcome: Study design: RCT. Quality score: 7.8/10.[1320,1361,1376, etc.]
Open source 91. Novel Chewable Pleuran-Based Supplement Decreases Respiratory Tract Infections in Children: A Randomised Controlled Trial.
RCT • 2025 • PubMed indexed study
PMID 41085920 from Advances in therapy.
Outcome: Study design: RCT. Quality score: 7.8/10.[1320,1361,1376, etc.]
Open source 92. Baker's yeast beta glucan supplementation was associated with an improved innate immune mRNA expression response after exercise.
RCT • 2024 • PubMed indexed study
PMID 39097177 from Methods (San Diego, Calif.).
Outcome: Study design: RCT. Quality score: 7.8/10.[1320,1361,1376, etc.]
Open source 93. Combined effect of polycan, a β-glucan from Aureobasidium pullulans, and regular resistance exercise on muscle strength, biomarkers, and fitness profiles in adults with relatively low skeletal muscle mass: a randomised controlled trial.
RCT • 2023 • PubMed indexed study
PMID 37350091 from Food & function.
Outcome: Study design: RCT. Quality score: 7.8/10.[1320,1361,1376, etc.]
Open source 94. Baker's yeast beta glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise.
RCT • 2013 • PubMed indexed study
PMID 23927572 from Journal of dietary supplements.
Outcome: Study design: RCT. Quality score: 7.8/10.[1320,1361,1376, etc.]
Open source 95. Effects of Nichi BRITE β-glucans as an onco-nutrition adjuvant in patients undergoing subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) for pancreatic, bile duct and duodenal malignancies: A clinical study.
RCT • 2025 • PubMed indexed study
PMID 40383031 from Nutrition (Burbank, Los Angeles County, Calif.).
Outcome: Study design: RCT. Quality score: 7.8/10.[1320,1361,1376, etc.]
Open source 96. The Prebiotic Effects of Oats on Blood Lipids, Gut Microbiota, and Short-Chain Fatty Acids in Mildly Hypercholesterolemic Subjects Compared With Rice: A Randomized, Controlled Trial.
RCT • 2021 • PubMed indexed study
PMID 34956218 from Frontiers in immunology.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 97. Effects of β-glucan and inulin consumption on postprandial appetite, energy intake and food consumption in healthy females: A randomized controlled trial.
RCT • 2022 • PubMed indexed study
PMID 34128426 from Nutrition and health.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 98. Potentially Beneficial Effects on Healthy Aging by Supplementation of the EPA-Rich Microalgae Phaeodactylum tricornutum or Its Supernatant-A Randomized Controlled Pilot Trial in Elderly Individuals.
RCT • 2022 • PubMed indexed study
PMID 36421994 from Marine drugs.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 99. Barley malt-based composition as a galactagogue - a randomized, controlled trial in preterm mothers.
RCT • 2021 • PubMed indexed study
PMID 33751522 from Ginekologia polska.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 100. Beneficial effects of novel aureobasidium pullulans strains produced beta-1,3-1,6 glucans on interleukin-6 and D-dimer levels in COVID-19 patients; results of a randomized multiple-arm pilot clinical study.
RCT • 2022 • PubMed indexed study
PMID 34840031 from Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 101. Serum Metabolomics Reveals Underlying Mechanisms of Cholesterol-Lowering Effects of Oat Consumption: A Randomized Controlled Trial in a Mildly Hypercholesterolemic Population.
RCT • 2021 • PubMed indexed study
PMID 33793078 from Molecular nutrition & food research.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 102. Primary care experience on Stimunex(®) gocce in children with recurrent respiratory infections: a real-world study during the COVID-19 pandemic era.
RCT • 2022 • PubMed indexed study
PMID 35527651 from Allergologia et immunopathologia.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 103. A Quality-of-Life Study in Healthy Adults Supplemented with Lentinex® Beta-Glucan of Shiitake Culinary-Medicinal Mushroom, Lentinus edodes (Agaricomycetes).
RCT • 2020 • PubMed indexed study
PMID 32749096 from International journal of medicinal mushrooms.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 104. Three novel prevention, diagnostic, and treatment options for COVID-19 urgently necessitating controlled randomized trials.
RCT • 2020 • PubMed indexed study
PMID 32534175 from Medical hypotheses.
Outcome: Study design: RCT. Quality score: 7.7/10.[1320,1361,1376, etc.]
Open source 105. Effects of oat β-glucan consumption at breakfast on ad libitum eating, appetite, glycemia, insulinemia and GLP-1 concentrations in healthy subjects.
RCT • 2018 • PubMed indexed study
PMID 29920323 from Appetite.
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 106. Molecular weight of barley β-glucan does not influence satiety or energy intake in healthy male subjects.
RCT • 2014 • PubMed indexed study
PMID 25106092 from Appetite.
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 107. Effect of consuming novel foods consisting high oleic canola oil, barley β-glucan, and DHA on cardiovascular disease risk in humans: the CONFIDENCE (Canola Oil and Fibre with DHA Enhanced) study - protocol for a randomized controlled trial.
RCT • 2015 • PubMed indexed study
PMID 26518870 from Trials.
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 108. Effect of cooked white rice with high β-glucan barley on appetite and energy intake in healthy Japanese subjects: a randomized controlled trial.
RCT • 2014 • PubMed indexed study
PMID 25139426 from Plant foods for human nutrition (Dordrecht, Netherlands).
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 109. Instant Oatmeal Increases Satiety and Reduces Energy Intake Compared to a Ready-to-Eat Oat-Based Breakfast Cereal: A Randomized Crossover Trial.
RCT • 2016 • PubMed indexed study
PMID 26273900 from Journal of the American College of Nutrition.
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 110. Acute effects of protein composition and fibre enrichment of yogurt consumed as snacks on appetite sensations and subsequent ad libitum energy intake in healthy men.
RCT • 2015 • PubMed indexed study
PMID 26394259 from Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 111. Follow-up formula consumption in 3- to 4-year-olds and respiratory infections: an RCT.
RCT • 2014 • PubMed indexed study
PMID 24843061 from Pediatrics.
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 112. Supplementation of Caricol®-Gastro reduces chronic gastritis disease associated pain.
RCT • 2018 • PubMed indexed study
PMID 29604620 from Neuro endocrinology letters.
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 113. [Comparison of a commercially available, formula-based nutritional therapy enriched with oats fiber with a non-formula isocaloric therapy to treat non-alcoholic fatty liver disease (NAFLD) - a randomized, controlled intervention trial].
RCT • 2018 • PubMed indexed study
PMID 30304749 from Zeitschrift fur Gastroenterologie.
Outcome: Study design: RCT. Quality score: 7.6/10.[1320,1361,1376, etc.]
Open source 114. Pleuran (β-glucan from Pleurotus ostreatus) supplementation, cellular immune response and respiratory tract infections in athletes.
RCT • 2011 • PubMed indexed study
PMID 21249381 from European journal of applied physiology.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 115. Baker's yeast beta-glucan supplement reduces upper respiratory symptoms and improves mood state in stressed women.
RCT • 2012 • PubMed indexed study
PMID 23378458 from Journal of the American College of Nutrition.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 116. beta-Glucan-enriched bread reduces energy intake and modifies plasma ghrelin and peptide YY concentrations in the short term.
RCT • 2009 • PubMed indexed study
PMID 19631705 from Appetite.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 117. Oat prevents obesity and abdominal fat distribution, and improves liver function in humans.
RCT • 2013 • PubMed indexed study
PMID 23371785 from Plant foods for human nutrition (Dordrecht, Netherlands).
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 118. Effect of Pleuran (β-glucan from Pleurotus ostreatus) supplementation on cellular immune response after intensive exercise in elite athletes.
RCT • 2010 • PubMed indexed study
PMID 21164546 from Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 119. Physiological effects of concentrated barley beta-glucan in mildly hypercholesterolemic adults.
RCT • 2008 • PubMed indexed study
PMID 18838533 from Journal of the American College of Nutrition.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 120. Sugar and dietary fibre composition influence, by different hormonal response, the satiating capacity of a fruit-based and a β-glucan-enriched beverage.
RCT • 2012 • PubMed indexed study
PMID 22057424 from Food & function.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 121. Serum lipids and postprandial glucose and insulin levels in hyperlipidemic subjects after consumption of an oat beta-glucan-containing ready meal.
RCT • 2008 • PubMed indexed study
PMID 18334815 from Annals of nutrition & metabolism.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 122. Oat ingestion reduces systolic and diastolic blood pressure in patients with mild or borderline hypertension: a pilot trial.
RCT • 2002 • PubMed indexed study
PMID 11978262 from The Journal of family practice.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 123. Effect of muesli with 4 g oat beta-glucan on postprandial blood glucose, gastric emptying and satiety in healthy subjects: a randomized crossover trial.
RCT • 2008 • PubMed indexed study
PMID 18978166 from Journal of the American College of Nutrition.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 124. Satiating effect of a barley beta-glucan-enriched snack.
RCT • 2010 • PubMed indexed study
PMID 20679146 from Journal of the American College of Nutrition.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 125. Acute effect of oatmeal on subjective measures of appetite and satiety compared to a ready-to-eat breakfast cereal: a randomized crossover trial.
RCT • 2013 • PubMed indexed study
PMID 24024772 from Journal of the American College of Nutrition.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 126. Immunomodulatory effect of pleuran (β-glucan from Pleurotus ostreatus) in children with recurrent respiratory tract infections.
RCT • 2013 • PubMed indexed study
PMID 23261366 from International immunopharmacology.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 127. Reduced serum cholesterol with dietary change using fat-modified and oat bran supplemented diets.
RCT • 1990 • PubMed indexed study
PMID 2154513 from Journal of the American Dietetic Association.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 128. Oat bran concentrate bread products improve long-term control of diabetes: a pilot study.
RCT • 1996 • PubMed indexed study
PMID 8948386 from Journal of the American Dietetic Association.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 129. The effect of strawberries in a cholesterol-lowering dietary portfolio.
RCT • 2008 • PubMed indexed study
PMID 19013285 from Metabolism: clinical and experimental.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 130. Four-week low-glycemic index breakfast with a modest amount of soluble fibers in type 2 diabetic men.
RCT • 2002 • PubMed indexed study
PMID 12077724 from Metabolism: clinical and experimental.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 131. Effect of eicosapentaenoic/docosahexaenoic fatty acids and soluble fibers on blood lipids of individuals classified into different levels of lipidemia.
RCT • 2007 • PubMed indexed study
PMID 17234506 from Nutrition (Burbank, Los Angeles County, Calif.).
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 132. Acute effects of oats and vitamin E on endothelial responses to ingested fat.
RCT • 2001 • PubMed indexed study
PMID 11165454 from American journal of preventive medicine.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 133. Consumption of oat milk for 5 weeks lowers serum cholesterol and LDL cholesterol in free-living men with moderate hypercholesterolemia.
RCT • 1999 • PubMed indexed study
PMID 10749030 from Annals of nutrition & metabolism.
Outcome: Study design: RCT. Quality score: 7.5/10.[1320,1361,1376, etc.]
Open source 134. Bioavailability of orange juice (poly)phenols: β-glucan-rich oat bran decreases urinary excretion of flavanone phase II metabolites and enhances excretion of microbiota-derived phenolic catabolites.
RCT • 2023 • PubMed indexed study
PMID 36764628 from Free radical biology & medicine.
Outcome: Study design: CONTROLLED_TRIAL. Quality score: 7.4/10.[1320,1361,1376, etc.]
Open source 135. Effects of β-glucan and Vitamin D Supplementation on Inflammatory Parameters in Patients with Diabetic Retinopathy.
RCT • 2019 • PubMed indexed study
PMID 29920123 from Journal of dietary supplements.
Outcome: Study design: CONTROLLED_TRIAL. Quality score: 7.0/10.[1320,1361,1376, etc.]
Open source 136. Fermented Fiber Supplements Are No Better Than Placebo for a Laxative Effect.
PUBMED • 2016 • PubMed indexed study
PMID 27680987 from Digestive diseases and sciences.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 6.4/10.[1320,1361,1376, etc.]
Open source 137. The benefit of secondary prevention with oat fiber in reducing future cardiovascular event among CAD patients after coronary intervention.
COHORT • 2019 • PubMed indexed study
PMID 30816213 from Scientific reports.
Outcome: Study design: COHORT. Quality score: 6.3/10.[1320,1361,1376, etc.]
Open source 138. The effect of cereal Β-glucan on body weight and adiposity: A review of efficacy and mechanism of action.
PUBMED • 2023 • PubMed indexed study
PMID 34727805 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.8/10.[1320,1361,1376, etc.]
Open source 139. Interaction between β-glucans and gut microbiota: a comprehensive review.
PUBMED • 2024 • PubMed indexed study
PMID 36975759 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.8/10.[1320,1361,1376, etc.]
Open source 140. Comparative study on static and dynamic digest characteristics of oat β-Glucan and β-Gluco-Oligosaccharides.
COHORT • 2024 • PubMed indexed study
PMID 39593365 from Food research international (Ottawa, Ont.).
Outcome: Study design: COHORT. Quality score: 5.8/10.[1320,1361,1376, etc.]
Open source 141. Effects of fungal based bioactive compounds on human health: Review paper.
PUBMED • 2024 • PubMed indexed study
PMID 36794421 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.8/10.[1320,1361,1376, etc.]
Open source 142. Cauliflower mushroom (Sparassis): a promising functional food with nutritional and medicinal properties.
PUBMED • 2026 • PubMed indexed study
PMID 40583786 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.8/10.[1320,1361,1376, etc.]
Open source 143. An encompassing review of meta-analyses and systematic reviews of the effect of oats on all-cause mortality, cardiovascular risk, diabetes risk, body weight/adiposity and gut health.
PUBMED • 2025 • PubMed indexed study
PMID 39137936 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.8/10.[1320,1361,1376, etc.]
Open source 144. A comparative evaluation of the kefir yeast Kluyveromyces marxianus A4 and sulfasalazine in ulcerative colitis: anti-inflammatory impact and gut microbiota modulation.
COHORT • 2024 • PubMed indexed study
PMID 38833212 from Food & function.
Outcome: Study design: COHORT. Quality score: 5.8/10.[1320,1361,1376, etc.]
Open source 145. β-glucan, "the knight of health sector": critical insights on physiochemical heterogeneities, action mechanisms and health implications.
PUBMED • 2022 • PubMed indexed study
PMID 33819119 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.7/10.[1320,1361,1376, etc.]
Open source 146. Evaluation of anti-inflammatory and immunoregulatory activities of Stimunex® and Stimunex D3® in human monocytes/macrophages stimulated with LPS or IL-4/IL-13.
COHORT • 2020 • PubMed indexed study
PMID 33080469 from Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.
Outcome: Study design: COHORT. Quality score: 5.7/10.[1320,1361,1376, etc.]
Open source 147. Vitamin D Treatment Sequence Is Critical for Transcriptome Modulation of Immune Challenged Primary Human Cells.
COHORT • 2021 • PubMed indexed study
PMID 34956186 from Frontiers in immunology.
Outcome: Study design: COHORT. Quality score: 5.7/10.[1320,1361,1376, etc.]
Outcome: Study design: COHORT. Quality score: 5.6/10.[1320,1361,1376, etc.]
Open source 149. Structural Characterization, Technological Functionality, and Physiological Aspects of Fungal β-D-glucans: A Review.
PUBMED • 2016 • PubMed indexed study
PMID 25830657 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.6/10.[1320,1361,1376, etc.]
Open source 150. Use of viscous fibres in beverages for appetite control: a review of studies.
PUBMED • 2015 • PubMed indexed study
PMID 26001088 from International journal of food sciences and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.6/10.[1320,1361,1376, etc.]
Open source 151. Effect of beta-glucan from oats and yeast on serum lipids.
PUBMED • 1999 • PubMed indexed study
PMID 10198754 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.5/10.[1320,1361,1376, etc.]
Open source 152. Biomedical issues of dietary fiber beta-glucan.
PUBMED • 2006 • PubMed indexed study
PMID 17043406 from Journal of Korean medical science.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.5/10.[1320,1361,1376, etc.]
Open source 153. Pleuran (β-glucan from Pleurotus ostreatus ): an effective nutritional supplement against upper respiratory tract infections?
PUBMED • 2012 • PubMed indexed study
PMID 23075555 from Medicine and sport science.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.5/10.[1320,1361,1376, etc.]
Open source 154. Avena sativa (Oat), a potential neutraceutical and therapeutic agent: an overview.
PUBMED • 2013 • PubMed indexed study
PMID 23072529 from Critical reviews in food science and nutrition.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.5/10.[1320,1361,1376, etc.]
Open source 155. Effect of beta-glucan level in oat fiber extracts on blood lipids in men and women.
COHORT • 1997 • PubMed indexed study
PMID 9013433 from Journal of the American College of Nutrition.
Outcome: Study design: COHORT. Quality score: 5.5/10.[1320,1361,1376, etc.]
Open source 156. Nutritional strategies to counter stress to the immune system in athletes, with special reference to football.
PUBMED • 2006 • PubMed indexed study
PMID 16766504 from Journal of sports sciences.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.5/10.[1320,1361,1376, etc.]
Open source 157. Effects of soy and other natural products on LDL:HDL ratio and other lipid parameters: a literature review.
COHORT • 2003 • PubMed indexed study
PMID 12772818 from Advances in therapy.
Outcome: Study design: COHORT. Quality score: 5.5/10.[1320,1361,1376, etc.]
Open source 158. Fibre: The Forgotten Carbohydrate in Sports Nutrition Recommendations.
PUBMED • 2025 • PubMed indexed study
PMID 39775524 from Sports medicine (Auckland, N.Z.).
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.4/10.[1320,1361,1376, etc.]
Open source 159. Dietary Supplements in the Management of Symptoms Associated With Autism Spectrum Disorder: A Scoping Review.
PUBMED • 2025 • PubMed indexed study
PMID 40581607 from Nutrition reviews.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.4/10.[1320,1361,1376, etc.]
Open source 160. Engineered Probiotic-Based Personalized Cancer Vaccine Potentiates Antitumor Immunity through Initiating Trained Immunity.
PUBMED • 2024 • PubMed indexed study
PMID 38009498 from Advanced science (Weinheim, Baden-Wurttemberg, Germany).
Outcome: Study design: OTHER. Quality score: 5.3/10.[1320,1361,1376, etc.]
Open source 161. Gastrointestinal Effects and Tolerance of Nondigestible Carbohydrate Consumption.
PUBMED • 2022 • PubMed indexed study
PMID 36041173 from Advances in nutrition (Bethesda, Md.).
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.3/10.[1320,1361,1376, etc.]
Open source 162. Glycoside hydrolase-mediated glucomannan catabolism in Segatella copri, a target of microbiota-directed foods for malnourished children.
PUBMED • 2025 • PubMed indexed study
PMID 41329729 from Proceedings of the National Academy of Sciences of the United States of America.
Outcome: Study design: OTHER. Quality score: 5.3/10.[1320,1361,1376, etc.]
Open source 163. Mechanistic Insights Into the Inhibitory Effects of Arabinoxylan and (1,3)(1,4)-β-Glucan on Starch Digestive Enzymes.
PUBMED • 2025 • PubMed indexed study
PMID 40285469 from Journal of food science.
Outcome: Study design: OTHER. Quality score: 5.3/10.[1320,1361,1376, etc.]
Open source 164. Per- and poly-fluoroalkyl substances (PFAS) in circulation in a Canadian population: their association with serum-liver enzyme biomarkers and piloting a novel method to reduce serum-PFAS.
PUBMED • 2025 • PubMed indexed study
PMID 40089764 from Environmental health : a global access science source.
Outcome: Study design: OTHER. Quality score: 5.3/10.[1320,1361,1376, etc.]
Open source 165. Microbial degradation of whole-grain complex carbohydrates and impact on short-chain fatty acids and health.
PUBMED • 2015 • PubMed indexed study
PMID 25770259 from Advances in nutrition (Bethesda, Md.).
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.2/10.[1320,1361,1376, etc.]
Open source 166. Anti-Inflammatory Effect of an O-2-Substituted (1-3)-β-D-Glucan Produced by Pediococcus parvulus 2.6 in a Caco-2 PMA-THP-1 Co-Culture Model.
PUBMED • 2022 • PubMed indexed study
PMID 35163449 from International journal of molecular sciences.
Outcome: Study design: OTHER. Quality score: 5.2/10.[1320,1361,1376, etc.]
Open source 167. Development of a whey protein spread enriched with β-glucan: an alternative for whey valorization.
PUBMED • 2020 • PubMed indexed study
PMID 31803934 from Journal of the science of food and agriculture.
Outcome: Study design: OTHER. Quality score: 5.2/10.[1320,1361,1376, etc.]
Open source 168. Fiber mixture-specific effect on distal colonic fermentation and metabolic health in lean but not in prediabetic men.
PUBMED • 2022 • PubMed indexed study
PMID 34923911 from Gut microbes.
Outcome: Study design: OTHER. Quality score: 5.2/10.[1320,1361,1376, etc.]
Open source 169. Mucosal immunity-mediated modulation of the gut microbiome by oral delivery of probiotics into Peyer's patches.
PUBMED • 2021 • PubMed indexed study
PMID 33980483 from Science advances.
Outcome: Study design: OTHER. Quality score: 5.2/10.[1320,1361,1376, etc.]
Open source 170. Potentials to alleviate coagulopathy and enhance microglial function of beta (β)- glucans, making them worth a clinical study for COVID-19's neurological sequalae.
PUBMED • 2021 • PubMed indexed study
PMID 34186495 from Journal of the neurological sciences.
Outcome: Study design: OTHER. Quality score: 5.2/10.[1320,1361,1376, etc.]
Open source 171. Harnessing Prebiotics to Improve Type 2 Diabetes Outcomes.
PUBMED • 2024 • PubMed indexed study
PMID 39458444 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 172. Cholesterol-lowering effects of oat β-glucan.
PUBMED • 2011 • PubMed indexed study
PMID 21631511 from Nutrition reviews.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 173. A Comprehensive Review on Dietary Polysaccharides as Prebiotics, Synbiotics, and Postbiotics in Infant Formula and Their Influences on Gut Microbiota.
PUBMED • 2024 • PubMed indexed study
PMID 39683515 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 174. Exploring the therapeutic potential of yeast β-glucan: Prebiotic, anti-infective, and anticancer properties - A review.
PUBMED • 2024 • PubMed indexed study
PMID 39522898 from International journal of biological macromolecules.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 175. Role of dietary beta-glucans in the prevention of the metabolic syndrome.
PUBMED • 2012 • PubMed indexed study
PMID 22835138 from Nutrition reviews.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 176. Lipid metabolism regulation by dietary polysaccharides with different structural properties.
PUBMED • 2024 • PubMed indexed study
PMID 38744359 from International journal of biological macromolecules.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 177. Immunonutrition support for athletes.
PUBMED • 2008 • PubMed indexed study
PMID 18522619 from Nutrition reviews.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 178. Phytosterols as functional food ingredients: linkages to cardiovascular disease and cancer.
PUBMED • 2009 • PubMed indexed study
PMID 19209468 from Current opinion in clinical nutrition and metabolic care.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 179. Non-starch carbohydrates as lever to improve cereal-based foods: The case of FODMAP and beta-glucans.
PUBMED • 2025 • PubMed indexed study
PMID 41005942 from Advances in food and nutrition research.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 180. Probiotics: a comprehensive approach toward health foods.
PUBMED • 2014 • PubMed indexed study
PMID 24237003 from Critical reviews in food science and nutrition.
Outcome: Study design: OTHER. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 181. Functional Properties of a High Protein Beverage Stabilized with Oat-β-Glucan.
PUBMED • 2018 • PubMed indexed study
PMID 29603228 from Journal of food science.
Outcome: Study design: OTHER. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 182. Advances in oligosaccharides and polysaccharides with different structures as wall materials for probiotics delivery: A review.
PUBMED • 2024 • PubMed indexed study
PMID 39217037 from International journal of biological macromolecules.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.1/10.[1320,1361,1376, etc.]
Open source 183. Beta Glucan: Supplement or Drug? From Laboratory to Clinical Trials.
PUBMED • 2019 • PubMed indexed study
PMID 30935016 from Molecules (Basel, Switzerland).
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.0/10.[1320,1361,1376, etc.]
Open source 184. Immunomodulating Effects of Fungal Beta-Glucans: From Traditional Use to Medicine.
PUBMED • 2021 • PubMed indexed study
PMID 33920583 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.0/10.[1320,1361,1376, etc.]
Open source 185. A comprehensive review on the impact of β-glucan metabolism by Bacteroides and Bifidobacterium species as members of the gut microbiota.
PUBMED • 2021 • PubMed indexed study
PMID 33864864 from International journal of biological macromolecules.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.0/10.[1320,1361,1376, etc.]
Open source 186. Therapeutic Potential of Various Plant-Based Fibers to Improve Energy Homeostasis via the Gut Microbiota.
PUBMED • 2021 • PubMed indexed study
PMID 34684471 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.0/10.[1320,1361,1376, etc.]
Open source 187. A Mechanistic Review on Medicinal Mushrooms-Derived Bioactive Compounds: Potential Mycotherapy Candidates for Alleviating Neurological Disorders.
PUBMED • 2020 • PubMed indexed study
PMID 32663897 from Planta medica.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.0/10.[1320,1361,1376, etc.]
Open source 188. Saccharomyces cerevisiae Yeast-Based Supplementation as a Galactagogue in Breastfeeding Women? A Review of Evidence from Animal and Human Studies.
PUBMED • 2021 • PubMed indexed study
PMID 33668808 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 5.0/10.[1320,1361,1376, etc.]
Open source 189. Cereal flours with Bacillus coagulans and beta-glucan: Technological properties and sensory acceptability.
PUBMED • 2024 • PubMed indexed study
PMID 38569414 from Food chemistry.
Outcome: Study design: OTHER. Quality score: 4.9/10.[1320,1361,1376, etc.]
Open source 190. Enhanced Bioavailability of Ferric Pyrophosphate Delivery System Constructed with β-Glucan and Casein Phosphopeptide.
PUBMED • 2025 • PubMed indexed study
PMID 40600440 from Journal of agricultural and food chemistry.
Outcome: Study design: OTHER. Quality score: 4.9/10.[1320,1361,1376, etc.]
Open source 191. The gut microbiota of healthy individuals remains resilient in response to the consumption of various dietary fibers.
PUBMED • 2024 • PubMed indexed study
PMID 39333601 from Scientific reports.
Outcome: Study design: OTHER. Quality score: 4.9/10.[1320,1361,1376, etc.]
Open source 192. Characterization of Water-Soluble Oxidized Paramylon and Its Hypoglycemic Effects by Alleviating Insulin Resistance.
PUBMED • 2025 • PubMed indexed study
PMID 40619873 from Journal of agricultural and food chemistry.
Outcome: Study design: OTHER. Quality score: 4.9/10.[1320,1361,1376, etc.]
Open source 193. Effect of extraction methods on physicochemical and prebiotic properties of adlay (Coix lachryma-jobi L. var. ma-yuen Stapf.) seed hull polysaccharides.
PUBMED • 2025 • PubMed indexed study
PMID 41076884 from Food chemistry.
Outcome: Study design: OTHER. Quality score: 4.9/10.[1320,1361,1376, etc.]
Open source 194. Effects of dietary fiber and its components on metabolic health.
PUBMED • 2010 • PubMed indexed study
PMID 22254008 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 195. Prebiotics: Ignored player in the fight against cancer.
PUBMED • 2023 • PubMed indexed study
PMID 37458148 from Cancer reports (Hoboken, N.J.).
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 196. Impact of Oats on Appetite Hormones and Body Weight Management: A Review.
PUBMED • 2023 • PubMed indexed study
PMID 36790719 from Current nutrition reports.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 197. The effect of beta-glucan supplementation on glycemic control and variability in adolescents with type 1 diabetes mellitus.
PUBMED • 2020 • PubMed indexed study
PMID 32971156 from Diabetes research and clinical practice.
Outcome: Study design: OTHER. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 198. Major cereal grain fibers and psyllium in relation to cardiovascular health.
PUBMED • 2013 • PubMed indexed study
PMID 23628720 from Nutrients.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 199. Association Between the Gut Microbiota and Alzheimer's Disease: An Update on Signaling Pathways and Translational Therapeutics.
PUBMED • 2025 • PubMed indexed study
PMID 39460901 from Molecular neurobiology.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 200. Improvement of sleep and melatonin in children with autism spectrum disorder after β-1,3/1,6-glucan consumption: An open-label prospective pilot clinical study.
PUBMED • 2022 • PubMed indexed study
PMID 35993920 from Brain and behavior.
Outcome: Study design: OTHER. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 201. Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males.
PUBMED • 2019 • PubMed indexed study
PMID 30692581 from Scientific reports.
Outcome: Study design: OTHER. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 202. Increase in the incidence of invasive bacterial infections following the COVID-19 pandemic: potential links with decreased herd trained immunity - a novel concept in medicine.
PUBMED • 2024 • PubMed indexed study
PMID 38967606 from Polish archives of internal medicine.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.8/10.[1320,1361,1376, etc.]
Open source 203. β-1,3/1,6-Glucans and Immunity: State of the Art and Future Directions.
PUBMED • 2021 • PubMed indexed study
PMID 32223047 from Molecular nutrition & food research.
Outcome: Study design: NARRATIVE_REVIEW. Quality score: 4.7/10.[1320,1361,1376, etc.]