Food
Lycopene-rich foods are linked to oxidative-stress and vascular markers.[1312,1500,2131, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
55/100
Moderate signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
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Classification: prioritize.[1141,1298,1312, etc.]
Best fit: Users with low carotenoid intake..[1141,1298,1312, etc.]
Goal alignment: Heart Health, Skin Hair, Longevity.[1141,1298,1312, etc.]
Classification
Prioritize
Evidence Tier
HIGH
Best Fit
Users with low carotenoid intake.
Primary Focus
Heart Health, Skin Hair
Clinical Depth
Humans: 411 • RCTs: 81 • Meta: 13
Cohort / Real-World
Cohort signals: 55
Safety Markers
Adverse signals: 16 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
411 total studies · 1 recent
Timeline
Total indexed
411
Human studies
411
In vitro / tissue
109
Randomized trials
81
Cohort signals
55
Safety adverse signals
16
Weighted direction score: 0 (Mixed / Neutral)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
411
Human studies
411
In vitro / tissue
109
Randomized trials
81
Cohort signals
55
Safety adverse signals
16
Meta-analyses
13
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
PMID 33131949 • 2021 May 1
Tomato and lycopene and multiple health outcomes: Umbrella review.
Food Chem
Open PubMedPMID 28129549 • 2017 Feb
Tomato and lycopene supplementation and cardiovascular risk factors: A systematic review and meta-analysis.
Atherosclerosis
Open PubMedPMID 23883692 • 2013
Lycopene/tomato consumption and the risk of prostate cancer: a systematic review and meta-analysis of prospective studies.
J Nutr Sci Vitaminol (Tokyo)
Open PubMedBenefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
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aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 411, RCT 81, meta 13, cohort 55.[1312,1500,2131, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33131949 from Food Chem.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,, etc.]
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
Composite of study volume, RCTs, and meta-analyses
PMID 35031434 • 2022 Mar
The effect of lycopene supplement from different sources on prostate specific antigen (PSA): A systematic review and meta-analysis of randomized controlled trials.
Complement Ther Med
Open PubMedPMID 37496241 • 2023
The Effects of Lycopene and Tomato Consumption on Cardiovascular Risk Factors in Adults: A Grade Assessment Systematic Review and Meta-analysis.
Curr Pharm Des
Open PubMedPMID 28799780 • 2019
Lycopene and tomato and risk of cardiovascular diseases: A systematic review and meta-analysis of epidemiological evidence.
Crit Rev Food Sci Nutr
Open PubMedPMID 12424331 • 2002 Nov
Lycopene and the lung.
Exp Biol Med (Maywood)
Open PubMedPMID 27406859 • 2017 Jun
Tomato-based randomized controlled trial in prostate cancer patients: Effect on PSA.
Clin Nutr
Open PubMedPMID 22854412 • 2012 Sep
Manipulating antioxidant intake in asthma: a randomized controlled trial.
Am J Clin Nutr
Open PubMedPMID 30239552 • 2018 Oct 1
Limited appearance of apocarotenoids is observed in plasma after consumption of tomato juices: a randomized human clinical trial.
Am J Clin Nutr
Open PubMedPMID 31130668 • 2019 May 25
Effect of 12-Week Daily Intake of the High-Lycopene Tomato (Solanum Lycopersicum), A Variety Named "PR-7", on Lipid Metabolism: A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study.
Nutrients
Open PubMedPMID 26202168 • 2015 Aug 28
A comparison of plasma and prostate lycopene in response to typical servings of tomato soup, sauce or juice in men before prostatectomy.
Br J Nutr
Open PubMedPMID 31900902 • 2019
Diet and Lifestyle in Prostate Cancer.
Adv Exp Med Biol
Open PubMedPMID 39033400 • 2024
Associations Between Dietary Intake of Tomato and Lycopene with All-Cause and Cancer-Specific Mortality in US Adults with Diabetes: Results From a Cohort Study.
Nutr Cancer
Open PubMedPMID 10050865 • 1999 Feb 17
Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature.
J Natl Cancer Inst
Open PubMedPMID 36583486 • 2023 Feb
Association between Tomato and Lycopene Consumption and Risk of All-Cause and Cause-Specific Mortality: Korean Genome and Epidemiology Study Cohort.
Mol Nutr Food Res
Open PubMedFallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=tomatoes%20and%20tomato%20products
Community Sources
PUBMED • 2017 • Human evidence curation set
PMID 28129549 from Atherosclerosis.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2013 • Human evidence curation set
PMID 23883692 from J Nutr Sci Vitaminol (Tokyo).
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35031434 from Complement Ther Med.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37496241 from Curr Pharm Des.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 28799780 from Crit Rev Food Sci Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2002 • Human evidence curation set
PMID 12424331 from Exp Biol Med (Maywood).
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 27406859 from Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2012 • Human evidence curation set
PMID 22854412 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 30239552 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31130668 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 26202168 from Br J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 31900902 from Adv Exp Med Biol.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39033400 from Nutr Cancer.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 1999 • Human evidence curation set
PMID 10050865 from J Natl Cancer Inst.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 36583486 from Mol Nutr Food Res.
Outcome: See linked PubMed abstract for methods and outcomes.[1312,1500,2131, etc.]
Open source