Food
Palatability and cooking stability can support adherence but increases saturated fat intake.[1475,1779,1990, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
27/100
Early signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
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Classification: case-dependent.[1063,1174,1475, etc.]
Best fit: Users prioritizing taste/adherence with otherwise high-quality diet patterns..[1063,1174,1475, etc.]
Goal alignment: Body Composition, Heart Health.[1063,1174,1475, etc.]
Classification
Case Dependent
Evidence Tier
HIGH
Best Fit
Users prioritizing taste/adherence with otherwise high-quality diet patterns.
Primary Focus
Body Composition, Heart Health
Clinical Depth
Humans: 149 • RCTs: 11 • Meta: 4
Cohort / Real-World
Cohort signals: 28
Safety Markers
Adverse signals: 3 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
149 total studies · 2 recent
Timeline
Total indexed
149
Human studies
149
Cohort signals
28
Randomized trials
11
In vitro / tissue
6
Meta-analyses
4
Weighted direction score: 0 (Mixed / Neutral)
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
149
Human studies
149
Cohort signals
28
Randomized trials
11
In vitro / tissue
6
Meta-analyses
4
Safety adverse signals
3
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 33471083 • 2021 Apr 6
Nut consumption and type 2 diabetes risk: a systematic review and meta-analysis of observational studies.
Am J Clin Nutr
Open PubMedPMID 27355649 • 2016
Is Butter Back? A Systematic Review and Meta-Analysis of Butter Consumption and Risk of Cardiovascular Disease, Diabetes, and Total Mortality.
PLoS One
Open PubMedPMID 33307550 • 2021 Jun 1
Association of Total Nut, Tree Nut, Peanut, and Peanut Butter Consumption with Cancer Incidence and Mortality: A Comprehensive Systematic Review and Dose-Response Meta-Analysis of Observational Studies.
Adv Nutr
Open PubMedPMID 26011901 • 2015 May
Effect of cheese consumption on blood lipids: a systematic review and meta-analysis of randomized controlled trials.
Nutr Rev
Open PubMedPMID 34656952 • 2021 Nov
Consumption of peanut products improves memory and stress response in healthy adults from the ARISTOTLE study: A 6-month randomized controlled trial.
Clin Nutr
Open PubMedPMID 41632974 • 2026 Feb
Effects of Peanut Butter Supplementation on Older Adults' Physical Function: A 6-Month Randomised Controlled Trial.
J Cachexia Sarcopenia Muscle
Open PubMedPMID 34794522 • 2022 Nov 14
Effects of diets rich in ghee or olive oil on cardiometabolic risk factors in healthy adults: a two-period, crossover, randomised trial.
Br J Nutr
Open PubMedPMID 20648041 • 2010 Oct
Effects of margarines and butter consumption on lipid profiles, inflammation markers and lipid transfer to HDL particles in free-living subjects with the metabolic syndrome.
Eur J Clin Nutr
Open PubMedPMID 38501177 • 2024 Jun 28
The effects of replacing ghee with rapeseed oil on liver steatosis and enzymes, lipid profile, insulin resistance and anthropometric measurements in patients with non-alcoholic fatty liver disease: a randomised controlled clinical trial.
Br J Nutr
Open PubMedPMID 17707980 • 2006 Feb
Effects of margarine and butter consumption on distribution of trans-18:1 fatty acid isomers and conjugated linoleic acid in major serum lipid classes in lactating women.
Lipids
Open PubMedPMID 28768652 • 2017 Sep
Nut and peanut butter consumption and the risk of esophageal and gastric cancer subtypes.
Am J Clin Nutr
Open PubMedPMID 32727726 • 2020 Oct
Nut and Peanut Butter Consumption and the Risk of Total Cancer: A Prospective Cohort Study.
Cancer Epidemiol Biomarkers Prev
Open PubMedPMID 30642454 • 2019 Feb
Nut and peanut butter consumption and the risk of lung cancer and its subtypes: A prospective cohort study.
Lung Cancer
Open PubMedPMID 11978580 • 2002 May 1
Prospective study of diet and pancreatic cancer in male smokers.
Am J Epidemiol
Open PubMedPMID 35044629 • 2022 Jan
Dairy Foods: Is Its Cardiovascular Risk Profile Changing?
Curr Atheroscler Rep
Open PubMedPMID 37226031 • 2023 Sep
Dairy Foods: Beneficial Effects of Fermented Products on Cardiometabolic Health.
Curr Nutr Rep
Open PubMedBenefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22butter%20and%20ghee%22%20(diet%20OR%20nutrition%20OR%20meals%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3Anutrition%20OR%20subreddit%3AScientificNutrition%20OR%20subreddit%3Aloseit%20OR%20subreddit%3AMealPrepSunday%20OR%20subreddit%3Aketo%20OR%20subreddit%3Afasting%20OR%20subreddit%3Amediterraneandiet%20OR%20subreddit%3Avegan%20OR%20subreddit%3Avegetarian%20OR%20subreddit%3Acarnivorediet%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity)
Fallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=butter%20and%20ghee
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
Community Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 149, RCT 11, meta 4, cohort 28.[1475,1779,1990, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33471083 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2016 • Human evidence curation set
PMID 27355649 from PLoS One.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 33307550 from Adv Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 26011901 from Nutr Rev.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34656952 from Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2026 • Human evidence curation set
PMID 41632974 from J Cachexia Sarcopenia Muscle.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 34794522 from Br J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2010 • Human evidence curation set
PMID 20648041 from Eur J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38501177 from Br J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2006 • Human evidence curation set
PMID 17707980 from Lipids.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 28768652 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2020 • Human evidence curation set
PMID 32727726 from Cancer Epidemiol Biomarkers Prev.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2019 • Human evidence curation set
PMID 30642454 from Lung Cancer.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2002 • Human evidence curation set
PMID 11978580 from Am J Epidemiol.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35044629 from Curr Atheroscler Rep.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37226031 from Curr Nutr Rep.
Outcome: See linked PubMed abstract for methods and outcomes.[1475,1779,1990, etc.]
Open source