Food
Fiber and monounsaturated fat combination improves satiety and lipid response in many contexts.[2757,2869,2986, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
100
Positive Lean • confidence Moderate
Safety Friction
41/100
Early signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 6 • links 25
Not medical advice. This product is for educational and informational purposes only. It does not diagnose, treat, cure, or prevent any disease and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of a qualified healthcare provider with any questions regarding a medical condition.
FDA disclaimer: These statements have not been evaluated by the Food and Drug Administration. Dietary supplements are not intended to diagnose, treat, cure, or prevent any disease. Results may vary. Not intended for use by pregnant or nursing women, individuals under 18, or those with known medical conditions without physician consultation.
If you are experiencing a medical emergency, call 911 or your local emergency number immediately.
Classification: prioritize.[187,1164,2757, etc.]
Best fit: Users replacing refined carbohydrates or processed fats..[187,1164,2757, etc.]
Goal alignment: Heart Health, Metabolic Health, Body Composition.[187,1164,2757, etc.]
Classification
Prioritize
Evidence Tier
HIGH
Best Fit
Users replacing refined carbohydrates or processed fats.
Primary Focus
Heart Health, Metabolic Health
Clinical Depth
Humans: 236 • RCTs: 49 • Meta: 17
Cohort / Real-World
Cohort signals: 44
Safety Markers
Adverse signals: 7 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
236 total studies · 6 recent
Timeline
Total indexed
236
Human studies
236
In vitro / tissue
64
Randomized trials
49
Cohort signals
44
Meta-analyses
17
Weighted direction score: 100 (Positive Lean)
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
236
Human studies
236
In vitro / tissue
64
Randomized trials
49
Cohort signals
44
Meta-analyses
17
Safety adverse signals
7
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 29018060 • 2018 Feb
Dietary supplements for treating osteoarthritis: a systematic review and meta-analysis.
Br J Sports Med
Open PubMedPMID 29596440 • 2018
Effectiveness of school food environment policies on children's dietary behaviors: A systematic review and meta-analysis.
PLoS One
Open PubMedPMID 37106252 • 2023 Aug
Fruit and vegetable consumption and the risk of hypertension: a systematic review and meta-analysis of prospective studies.
Eur J Nutr
Open PubMedPMID 36565850 • 2024 Feb
Avocado Consumption and Cardiometabolic Health: A Systematic Review and Meta-Analysis.
J Acad Nutr Diet
Open PubMedPMID 35405602 • 2022 Jun
Can avocado intake improve weight loss in adults with excess weight? A systematic review and meta-analysis of randomized controlled trials.
Nutr Res
Open PubMedPMID 29635493 • 2018 Apr 1
Avocado consumption and risk factors for heart disease: a systematic review and meta-analysis.
Am J Clin Nutr
Open PubMedPMID 38040019 • 2024 Feb
The effect of expectancy versus actual gluten intake on gastrointestinal and extra-intestinal symptoms in non-coeliac gluten sensitivity: a randomised, double-blind, placebo-controlled, international, multicentre study.
Lancet Gastroenterol Hepatol
Open PubMedPMID 39128497 • 2024 Oct
Effect of daily avocado consumption for 6 mo compared with habitual diet on red blood cell fatty acid profiles and association with cardiometabolic risk factors in individuals with abdominal obesity: a randomized trial.
Am J Clin Nutr
Open PubMedPMID 35700149 • 2022 Aug 9
Avocado Consumption for 12 Weeks and Cardiometabolic Risk Factors: A Randomized Controlled Trial in Adults with Overweight or Obesity and Insulin Resistance.
J Nutr
Open PubMedPMID 37344091 • 2023 Aug
The impact of avocado intake on anthropometric measures among Hispanic/Latino children and adolescents: A cluster randomized controlled trial.
Clin Nutr ESPEN
Open PubMedPMID 40139076 • 2025 Apr
Full-fat versus non-fat yogurt consumption improves glucose homeostasis and metabolic hormone regulation in individuals with prediabetes: A randomized-controlled trial.
Nutr Res
Open PubMedPMID 39905430 • 2025 Feb 4
Efficacy of an avocado-based Mediterranean diet on serum lipids for secondary prevention after ischemic stroke: a randomized phase 2 controlled pilot trial.
Lipids Health Dis
Open PubMedPMID 28267855 • 2017 Mar 7
Association Between Dietary Factors and Mortality From Heart Disease, Stroke, and Type 2 Diabetes in the United States.
JAMA
Open PubMedPMID 35352568 • 2022 Apr 5
Avocado Consumption and Risk of Cardiovascular Disease in US Adults.
J Am Heart Assoc
Open PubMedPMID 39486625 • 2024 Dec
Effects of Varying Protein Amounts and Types on Diet-Induced Thermogenesis: A Systematic Review and Meta-Analysis.
Adv Nutr
Open PubMedPMID 34649831 • 2021 Nov-Dec
Saturated fats and cardiovascular health: Current evidence and controversies.
J Clin Lipidol
Open PubMedBenefit reports: 2
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 4
Signal confidence: 0.47
Benefits
Adverse
No Effect
Community confidence 0.47 with mentions: benefit 2, adverse 0, no-effect 0.
Subreddit coverage: MealPrepSunday, ScientificNutrition, loseit.
post • r/ScientificNutrition • unclear
Effects of Increasing Total Fruit Intake With Avocado and Mango on Endothelial Function and Cardiometabolic Risk Factors in Adults With Prediabetes
Open mentionpost • r/loseit • unclear
Are skinny people always hungry? If I eat whenever I feel hunger, even though they are "healthy" meals* I WILL gain weight. **(for breakfast I usually have 1 whole wheat toast, 1/4 to 1/2 avocado, 1 scrambled egg and coffee with milk. Then…
Open mentionpost • r/MealPrepSunday • benefit
What I eat every day, 3x a day, for 2 years now (caveats in description). Hello Reddit, I have been on a consistent diet for the past two years now and wanted to share my routine in hopes of providing valuable information, motivation, and/…
Open mentionpost • r/loseit • benefit
What’s a diet meal or snack you could every day? I was thinking we could share our favorite diet meals and snacks. Help inspire each other, maybe. Absolute favorite, I could eat daily? Sometimes twice daily? Cottage cheese, ground beef, sw…
Open mentioncomment • r/ScientificNutrition • unclear
Which foods did the avocado and mango replace? Other wholefoods or highly processed foods?
Open mentioncomment • r/ScientificNutrition • unclear
**Background** Low fruit intake is a global risk factor for cardiometabolic diseases. This study sought to investigate vascular and metabolic effects of increasing total and select fruit intake in adults with prediabetes. **Methods** This …
Open mentionEvidence Sources
Community Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 236, RCT 49, meta 17, cohort 44.[2757,2869,2986, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29018060 from Br J Sports Med.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29596440 from PLoS One.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37106252 from Eur J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 36565850 from J Acad Nutr Diet.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35405602 from Nutr Res.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29635493 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38040019 from Lancet Gastroenterol Hepatol.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39128497 from Am J Clin Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35700149 from J Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37344091 from Clin Nutr ESPEN.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40139076 from Nutr Res.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 39905430 from Lipids Health Dis.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2017 • Human evidence curation set
PMID 28267855 from JAMA.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35352568 from J Am Heart Assoc.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39486625 from Adv Nutr.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34649831 from J Clin Lipidol.
Outcome: See linked PubMed abstract for methods and outcomes.[2757,2869,2986, etc.]
Open source