Food
Dose-dependent alcohol exposure impairs sleep architecture and increases chronic disease risk.[1608,2398,2447, etc.]
Superscript reference numbers link to the Sources bibliography.
Composite Rating
Blends evidence depth, community direction, safety friction, and completeness.
Evidence Intensity
100/100
High depth from human/RCT/meta counts
Community Direction
0
Mixed / Neutral • confidence Minimal
Safety Friction
100/100
High signal from adverse/interaction markers
Data Completeness
100%
Studies 16 • mentions 0 • links 25
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Classification: limit.[1055,1160,1608, etc.]
Best fit: Users with sleep, mood, or metabolic goals..[1055,1160,1608, etc.]
Goal alignment: Sleep, Longevity, Metabolic Health, Mood.[1055,1160,1608, etc.]
Classification
Limit
Evidence Tier
HIGH
Best Fit
Users with sleep, mood, or metabolic goals.
Primary Focus
Sleep, Longevity
Clinical Depth
Humans: 49,448 • RCTs: 2,153 • Meta: 1,000
Cohort / Real-World
Cohort signals: 10,236
Safety Markers
Adverse signals: 966 • Interactions: 0
Freshness, trend, and study timeline for this item
Status
Trend
→ Stable evidence base
Depth
49448 total studies · 4 recent
Timeline
Total indexed
49,448
Human studies
49,448
Cohort signals
10,236
Randomized trials
2,153
Meta-analyses
1,000
Safety adverse signals
966
Weighted direction score: 0 (Mixed / Neutral)
No directional mention volume was resolved; fallback profile metadata is shown in other sections.
High when there are >=2 human meta-analyses, or strong human trial/cohort volume with substantial human literature.
Total indexed
49,448
Human studies
49,448
Cohort signals
10,236
Randomized trials
2,153
Meta-analyses
1,000
Safety adverse signals
966
In vitro / tissue
457
Animal-only studies
0
Distribution of evidence by study design strength
Evidence Strength: High
Composite of study volume, RCTs, and meta-analyses
PMID 25422909 • 2015 Feb 3
Alcohol consumption and site-specific cancer risk: a comprehensive dose-response meta-analysis.
Br J Cancer
Open PubMedPMID 37905315 • 2023
Cancer risk based on alcohol consumption levels: a comprehensive systematic review and meta-analysis.
Epidemiol Health
Open PubMedPMID 33524598 • 2022 Jun
Risk Factors for Early-Onset Colorectal Cancer: A Systematic Review and Meta-analysis.
Clin Gastroenterol Hepatol
Open PubMedPMID 38864208 • 2024 Aug
Alcohol Intake and Risk of Hypertension: A Systematic Review and Dose-Response Meta-Analysis of Nonexperimental Cohort Studies.
Hypertension
Open PubMedPMID 38030217 • 2023 Nov 29
Social media use and health risk behaviours in young people: systematic review and meta-analysis.
BMJ
Open PubMedPMID 35639552 • 2022 Nov 2
Comparison of dietary and physical activity behaviors in women with and without polycystic ovary syndrome: a systematic review and meta-analysis of 39 471 women.
Hum Reprod Update
Open PubMedPMID 37991022 • 2023 Nov 22
Effects of dulaglutide on alcohol consumption during smoking cessation.
JCI Insight
Open PubMedPMID 29043911 • 2018 Jan
Dutch courage? Effects of acute alcohol consumption on self-ratings and observer ratings of foreign language skills.
J Psychopharmacol
Open PubMedPMID 1541032 • 1992
Alcohol and hypertension.
Clin Exp Hypertens A
Open PubMedPMID 40110868 • 2025 Sep-Oct 01
Acute Alcohol Consumption Reduces Uncertainty Choices.
J Addict Med
Open PubMedPMID 38026297 • 2023
Peer-led BASICS intervention to reduce alcohol consumption and alcohol-related consequences among university students: a randomized controlled trial.
Front Public Health
Open PubMedPMID 39275279 • 2024 Sep 3
Consumption of Sylimarin, Pyrroloquinoline Quinone Sodium Salt and Myricetin: Effects on Alcohol Levels and Markers of Oxidative Stress-A Pilot Study.
Nutrients
Open PubMedPMID 35333364 • 2022 Mar 1
Association of Habitual Alcohol Intake With Risk of Cardiovascular Disease.
JAMA Netw Open
Open PubMedPMID 25741455 • 2015 Mar
Alcohol Consumption and Obesity: An Update.
Curr Obes Rep
Open PubMedPMID 34684583 • 2021 Oct 13
Evidence Update on the Relationship between Diet and the Most Common Cancers from the European Prospective Investigation into Cancer and Nutrition (EPIC) Study: A Systematic Review.
Nutrients
Open PubMedPMID 38971533 • 2024 Dec
Low-to-moderate alcohol consumption is associated with increased fibrosis in individuals with metabolic dysfunction-associated steatotic liver disease.
J Hepatol
Open PubMedBenefit reports: 0
Adverse reports: 0
No-effect reports: 0
Mixed reports: 0
Unclear reports: 0
Signal confidence: 0.00
Benefits
Adverse
No Effect
Community confidence 0.00 with mentions: benefit 0, adverse 0, no-effect 0.
Search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=8&q=%22alcohol%22%20(diet%20OR%20nutrition%20OR%20meals%20OR%20side%20effects%20OR%20experience%20OR%20results)%20(subreddit%3Anutrition%20OR%20subreddit%3AScientificNutrition%20OR%20subreddit%3Aloseit%20OR%20subreddit%3AMealPrepSunday%20OR%20subreddit%3Aketo%20OR%20subreddit%3Afasting%20OR%20subreddit%3Amediterraneandiet%20OR%20subreddit%3Avegan%20OR%20subreddit%3Avegetarian%20OR%20subreddit%3Acarnivorediet%20OR%20subreddit%3Abiohackers%20OR%20subreddit%3Alongevity)
Fallback search fetch failed: Failed to fetch after retries: https://old.reddit.com/search.json?raw_json=1&sort=relevance&t=year&limit=12&q=alcohol
aggregate • unclear
No directional first-hand mentions captured in the current community corpus; source links are retained for traceability.
Open mentionEvidence Sources
Community Sources
PUBMED • Humans + preclinical triage
Counts from structured PubMed query set for diet/intake context.
Outcome: Humans 49448, RCT 2153, meta 1000, cohort 10236.[1608,2398,2447, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 25422909 from Br J Cancer.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37905315 from Epidemiol Health.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 33524598 from Clin Gastroenterol Hepatol.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38864208 from Hypertension.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 38030217 from BMJ.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35639552 from Hum Reprod Update.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 37991022 from JCI Insight.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2018 • Human evidence curation set
PMID 29043911 from J Psychopharmacol.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 1992 • Human evidence curation set
PMID 1541032 from Clin Exp Hypertens A.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2025 • Human evidence curation set
PMID 40110868 from J Addict Med.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2023 • Human evidence curation set
PMID 38026297 from Front Public Health.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 39275279 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2022 • Human evidence curation set
PMID 35333364 from JAMA Netw Open.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2015 • Human evidence curation set
PMID 25741455 from Curr Obes Rep.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2021 • Human evidence curation set
PMID 34684583 from Nutrients.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open sourcePUBMED • 2024 • Human evidence curation set
PMID 38971533 from J Hepatol.
Outcome: See linked PubMed abstract for methods and outcomes.[1608,2398,2447, etc.]
Open source